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Chin Wee Tan
Chin Wee Tan
Senior Post-doc Fellow, WEHI
Dirección de correo verificada de wehi.edu.au
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Imbalance of the renin–angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?
G Mayur, R Simon G, T Chris, S Claire, B Duygu, V Elena, B Louise M, ...
Gut, 2019
1912019
Wnt signalling pathway parameters for mammalian cells
CW Tan, BS Gardiner, Y Hirokawa, MJ Layton, DW Smith, AW Burgess
PLoS ONE 7 (2), e31882, 2012
1262012
Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt–β-catenin–mediated intestinal tumor growth and regeneration
TJ Phesse, M Buchert, E Stuart, DJ Flanagan, M Faux, S Afshar-Sterle, ...
Science Signaling 7 (345), ra92, 2014
752014
Specification, annotation, visualization and simulation of a large rule-based model for ERBB receptor signaling
MS Creamer, EC Stites, M Aziz, JA Cahill, CW Tan, ME Berens, H Han, ...
BMC systems biology 6, 1-14, 2012
492012
Colon Cryptogenesis: Asymmetric Budding
CW Tan, Y Hirokawa, BS Gardiner, DW Smith, AW Burgess
PLoS ONE 8 (10), e78519, 2013
432013
Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures
A Kulasinghe, CW Tan, AFR dos Santos Miggiolaro, J Monkman, ...
European Respiratory Journal 59 (6), 2022
382022
Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth
P Thilakasiri, J Huynh, AR Poh, CW Tan, TL Nero, K Tran, AC Parslow, ...
EMBO molecular medicine 11 (4), e9539, 2019
382019
Colonic myofibroblast cell line stimulates colonoid formation
Y Hirokawa, KHY Yip, CW Tan, AW Burgess
American Journal of Physiology-Gastrointestinal and Liver Physiology 306 (7 …, 2014
342014
Discrete element framework for modelling extracellular matrix, deformable cells and subcellular components
BS Gardiner, KKL Wong, GR Joldes, AJ Rich, CW Tan, AW Burgess, ...
PLoS computational biology 11 (10), e1004544, 2015
332015
Analysis of Wnt signaling beta-catenin spatial dynamics in HEK293T cells
CW Tan, BS Gardiner, Y Hirokawa, DW Smith, AW Burgess
BMC Systems Biology 8 (44), 2014
332014
Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts
HYK Yip, CW Tan, Y Hirokawa, AW Burgess
PLoS One 13 (6), e0199412, 2018
282018
Transcriptomic profiling of cardiac tissues from SARS-CoV-2 patients identifies DNA damage
A Kulasinghe, N Liu, CW Tan, J Monkman, JE Sinclair, DD Bhuva, ...
Immunology, 2022
232022
IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study
M Shojaei, A Shamshirian, J Monkman, L Grice, M Tran, CW Tan, ...
Frontiers in Immunology 13, 1060438, 2023
212023
Mathematical model of TGF-βsignalling: feedback coupling is consistent with signal switching
S Khatibi, HJ Zhu, J Wagner, CW Tan, JH Manton, AW Burgess
BMC systems biology 11, 1-15, 2017
212017
LRIG1 extracellular domain: Structure and Function Analysis
Y Xu, P Soo, F Walker, HH Zhang, N Redpath, CW Tan, NA Nicola, ...
Journal of Molecular Biology, 2015
212015
Analysis of Wnt signalling dynamics during colon crypt development in 3D culture
CW Tan, Y Hirokawa, AW Burgess
Scientific Reports 5, e11036, 2015
172015
A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations
M Buchert, F Rohde, M Eissmann, N Tebbutt, B Williams, CW Tan, ...
Disease Models & Mechanisms 8 (11), 1361-1373, 2015
162015
Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine
Y Hirokawa, J Clarke, M Palmieri, T Tan, D Mouradov, S Li, C Lin, F Li, ...
Communications biology 4 (1), 1067, 2021
142021
Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer
PM Nguyen, LF Dagley, A Preaudet, N Lam, M Giam, KY Fung, K Aizel, ...
Cell Death & Differentiation 27 (2), 742-757, 2020
122020
First-in-class KAT6A/KAT6B inhibitor CTx-648 (PF-9363) demonstrates potent anti-tumor activity in ER+ breast cancer with KAT6A dysregulation
American Association for Cancer Research 81 (13 Supplement), 1130-1130, 2021
11*2021
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