Andres Norambuena
Andres Norambuena
Senior Scientist.University of Virginia
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Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease
ME Seward, E Swanson, A Norambuena, A Reimann, JN Cochran, R Li, ...
Journal of cell science 126 (5), 1278-1286, 2013
Apical sorting of a voltage- and Ca2+-activated K+ channel α-subunit in Madin-Darby canine kidney cells is independent of N-glycosylation
M Bravo-Zehnder, P Orio, A Norambuena, M Wallner, P Meera, L Toro, ...
Proceedings of the National Academy of Sciences 97 (24), 13114-13119, 2000
Galectin-8 induces apoptosis in Jurkat T cells by phosphatidic acid-mediated ERK1/2 activation supported by protein kinase A down-regulation
A Norambuena, C Metz, L Vicuña, A Silva, E Pardo, C Oyanadel, ...
Journal of biological chemistry 284 (19), 12670-12679, 2009
RalA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling
N Balasubramanian, JA Meier, DW Scott, A Norambuena, MA White, ...
Current Biology 20 (1), 75-79, 2010
mTOR and neuronal cell cycle reentry: How impaired brain insulin signaling promotes Alzheimer's disease
A Norambuena, H Wallrabe, L McMahon, A Silva, E Swanson, SS Khan, ...
Alzheimer's & Dementia 13 (2), 152-167, 2017
A novel lysosome‐to‐mitochondria signaling pathway disrupted by amyloid‐β oligomers
A Norambuena, H Wallrabe, R Cao, DB Wang, A Silva, Z Svindrych, ...
The EMBO journal 37 (22), e100241, 2018
Effects of integrin-mediated cell adhesion on plasma membrane lipid raft components and signaling
A Norambuena, MA Schwartz
Molecular biology of the cell 22 (18), 3456-3464, 2011
Regulation of Rac1 translocation and activation by membrane domains and their boundaries
K Moissoglu, V Kiessling, C Wan, BD Hoffman, A Norambuena, LK Tamm, ...
Journal of cell science 127 (11), 2565-2576, 2014
Reduced brain insulin signaling: a seminal process in Alzheimer's disease pathogenesis
GS Bloom, JS Lazo, A Norambuena
Neuropharmacology 136, 192-195, 2018
Phosphatidic acid induces ligand-independent epidermal growth factor receptor endocytic traffic through PDE4 activation
A Norambuena, C Metz, JE Jung, A Silva, C Otero, J Cancino, C Retamal, ...
Molecular Biology of the Cell 21 (16), 2916-2929, 2010
P2Y1 receptor activation elicits its partition out of membrane rafts and its rapid internalization from human blood vessels: implications for receptor signaling
A Norambuena, MI Poblete, MV Donoso, CS Espinoza, A Gonzalez, ...
Molecular pharmacology 74 (6), 1666-1677, 2008
Aberrant neuronal cell cycle re-entry: The pathological confluence of Alzheimer’s disease and brain insulin resistance, and its relation to cancer
MM Koseoglu, A Norambuena, ER Sharlow, JS Lazo, GS Bloom
Journal of Alzheimer's Disease 67 (1), 1-11, 2019
A small molecule screen exposes mTOR signaling pathway involvement in radiation-induced apoptosis
ER Sharlow, S Leimgruber, A Lira, MJ McConnell, A Norambuena, ...
ACS chemical biology 11 (5), 1428-1437, 2016
Epidermal growth factor receptor endocytic traffic perturbation by phosphatidate phosphohydrolase inhibition: new strategy against cancer
R Shaughnessy, C Retamal, C Oyanadel, A Norambuena, A López, ...
The FEBS Journal 281 (9), 2172-2189, 2014
Sorting competition with membrane-permeable peptides in intact epithelial cells revealed discrimination of transmembrane proteins not only at the trans-Golgi network but also …
A Soza, A Norambuena, J Cancino, E de la Fuente, P Henklein, ...
Journal of Biological Chemistry 279 (17), 17376-17383, 2004
UTP controls cell surface distribution and vasomotor activity of the human P2Y2 receptor through an epidermal growth factor receptor-transregulated mechanism
A Norambuena, F Palma, MI Poblete, MV Donoso, E Pardo, A González, ...
Journal of biological chemistry 285 (5), 2940-2950, 2010
SOD1 mediates lysosome-to-mitochondria communication and its dysregulation by amyloid-β oligomers
GSB Andrés Norambuena, Xuehan Sun, Horst Wallrabe, Ruofan Cao, Naidi Sun ...
Neurobiology of Disease 169 (, 2022
P2X1 receptors localized in lipid rafts mediate ATP motor responses in the human vas deferens longitudinal muscles
MV Donoso, A Norambuena, C Navarrete, I Poblete, A Velasco, ...
Biology of Reproduction 90 (2), 23, 1-10, 2014
Alzheimer’s disease as a metabolic disorder
GS Bloom, A Norambuena
OCL 25 (4), D403, 2018
A Novel Communication Pathway Between Lysosomes and Mitochondria Is Disrupted in Alzheimer’s Disease
A Norambuena, GS Bloom
Contact 2, 2515256419865859, 2019
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