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terance hart
terance hart
Director of Research
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Some observations concerning the S-nitroso and S-phenylsulphonyl derivatives of L-cysteine and glutathione
TW Hart
Tetrahedron Letters 26 (16), 2013-2016, 1985
4891985
Synthesis and biological activity of trans-(.+-.)-N-methyl-2-(3-pyridyl)-2-tetrahydrothiopyrancarbothioamide 1-oxide (RP 49356) and analogs: a new class of potassium channel opener
TJ Brown, RF Chapman, DC Cook, TW Hart, IM McLay, R Jordan, ...
Journal of medicinal chemistry 35 (20), 3613-3624, 1992
571992
Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas
T Hart, AT Macias, K Benwell, T Brooks, J D’Alessandro, P Dokurno, ...
Bioorganic & medicinal chemistry letters 19 (15), 4241-4244, 2009
442009
Regioselective epoxide-carbonyl rearrangements: A ring enlargement of cyclobutanones to cyclopentanones.
TW Hart, MT Comte
Tetrahedron letters 26 (22), 2713-2716, 1985
361985
Total synthesis of (±)-prostagladin D 1: use of triethylsilyl protecting groups
TW Hart, DA Metcalfe, F Scheinmann
Journal of the Chemical Society, Chemical Communications, 156-157, 1979
331979
Overcoming hERG issues for brain-penetrating cathepsin S inhibitors: 2-cyanopyrimidines. Part 2
O Irie, T Kosaka, M Kishida, J Sakaki, K Masuya, K Konishi, F Yokokawa, ...
Bioorganic & medicinal chemistry letters 18 (19), 5280-5284, 2008
322008
Sulfonamide derivatives
TW Hart, TJ Ritchie
US Patent 7,109,203, 2006
312006
The synthesis of RP 66471. A potent potassium channel opener.
TW Hart, D Guillochon, G Perrier, BW Sharp, MP Toft, B Vacher, ...
Tetrahedron letters 33 (47), 7211-7214, 1992
221992
Thiolsulphonate derivatives of amino acids
TW Hart, MB Vine, NR Walden
Tetrahedron letters 26 (32), 3879-3882, 1985
201985
The synthesis of RP 65479 a novel, potent potassium channel opener.
TW Hart, D Guillochon, G Perrier, BW Sharp, B Vacher
Tetrahedron letters 33 (35), 5117-5120, 1992
191992
The design and synthesis of inhibitors of the cysteinyl protease, Der p I
J Billson, J Clark, SP Conway, T Hart, T Johnson, SP Langston, M Ramjee, ...
Bioorganic & medicinal chemistry letters 8 (9), 993-998, 1998
181998
Versatile intramolecular reactions starting from a conformationally restricted epoxyalcohol
TW Hart, B Vacher
Tetrahedron letters 33 (21), 3009-3012, 1992
171992
Quinazolinone derivatives useful as anti-hyperalgesic agents
AJ Culshaw, EK Dziadulewicz, A Hallett, TW Hart
US Patent App. 11/950,079, 2008
13*2008
New drug targets in inflammation and immunomodulation
T Hart, A Lamont, D Williams
Drug Discovery Today 3 (11), 516-521, 1998
131998
Fatty acid amide hydrolase inhibitors. 3: Tetra-substituted azetidine ureas with in vivo activity
SD Roughley, H Browne, AT Macias, K Benwell, T Brooks, J D’Alessandro, ...
Bioorganic & medicinal chemistry letters 22 (2), 901-906, 2012
122012
Azetidine derivatives
S Roughley, S Walls, T Hart, R Parsons, P Brough, C Graham, A Macias
112009
Preparation of 2-substituted-4-monoketals of benzoquinone
TW Hart, F Scheinmann
Tetrahedron Letters 21 (23), 2295-2296, 1980
111980
Azetidine derivatives as FAAH inhibitors
S Roughley, S Walls, T Hart, R Parsons, P Brough, C Graham, A Macias
US Patent 8,450,346, 2013
92013
Intramolecular thioamide participation reactions
TW Hart, B Vacher
Tetrahedron letters 33 (47), 7215-7218, 1992
91992
Quinazolinone derivatives useful as vanilloid antagonists
TJ Ritchie
US Patent 7,960,399, 2011
72011
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