|A data-driven approach to preprocessing Illumina 450K methylation array data|
R Pidsley, CC Y Wong, M Volta, K Lunnon, J Mill, LC Schalkwyk
BMC genomics 14 (1), 1-10, 2013
|Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration|
C Cunningham, DC Wilcockson, S Campion, K Lunnon, VH Perry
Journal of Neuroscience 25 (40), 9275-9284, 2005
|Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci|
PL De Jager, G Srivastava, K Lunnon, J Burgess, LC Schalkwyk, L Yu, ...
Nature neuroscience 17 (9), 1156-1163, 2014
|Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood|
MN Davies, M Volta, R Pidsley, K Lunnon, A Dixit, S Lovestone, C Coarfa, ...
Genome biology 13 (6), 1-14, 2012
|Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease|
C Cunningham, S Campion, K Lunnon, CL Murray, JFC Woods, ...
Biological psychiatry 65 (4), 304-312, 2009
|Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease|
K Lunnon, R Smith, E Hannon, PL De Jager, G Srivastava, M Volta, ...
Nature neuroscience 17 (9), 1164-1170, 2014
|Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease|
M Thambisetty, A Simmons, L Velayudhan, A Hye, J Campbell, Y Zhang, ...
Archives of general psychiatry 67 (7), 739-748, 2010
|Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes|
E Hannon, K Lunnon, L Schalkwyk, J Mill
Epigenetics 10 (11), 1024-1032, 2015
|Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway|
R Killick, EM Ribe, R Al-Shawi, B Malik, C Hooper, C Fernandes, ...
Molecular psychiatry 19 (1), 88-98, 2014
|Plasma proteins predict conversion to dementia from prodromal disease|
A Hye, J Riddoch-Contreras, AL Baird, NJ Ashton, C Bazenet, R Leung, ...
Alzheimer's & Dementia 10 (6), 799-807. e2, 2014
|A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status|
S Sood, IJ Gallagher, K Lunnon, E Rullman, A Keohane, H Crossland, ...
Genome biology 16, 1-17, 2015
|Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease|
SJ Furney, A Simmons, G Breen, I Pedroso, K Lunnon, P Proitsi, ...
Molecular psychiatry 16 (11), 1130-1138, 2011
|Inflammatory proteins in plasma are associated with severity of Alzheimer’s disease|
R Leung, P Proitsi, A Simmons, K Lunnon, A Güntert, D Kronenberg, ...
PloS one 8 (6), e64971, 2013
|Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood|
K Lunnon, Z Ibrahim, P Proitsi, A Lourdusamy, S Newhouse, M Sattlecker, ...
Journal of Alzheimer's disease 30 (3), 685-710, 2012
|A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex|
SJ Marzi, SK Leung, T Ribarska, E Hannon, AR Smith, E Pishva, ...
Nature neuroscience 21 (11), 1618-1627, 2018
|Systemic inflammation modulates Fc receptor expression on microglia during chronic neurodegeneration|
K Lunnon, JL Teeling, AL Tutt, MS Cragg, MJ Glennie, VH Perry
The Journal of Immunology 186 (12), 7215-7224, 2011
|Mitochondrial genes are altered in blood early in Alzheimer's disease|
K Lunnon, A Keohane, R Pidsley, S Newhouse, J Riddoch-Contreras, ...
Neurobiology of aging 53, 36-47, 2017
|Elevated DNA methylation across a 48‐kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology|
RG Smith, E Hannon, PL De Jager, L Chibnik, SJ Lott, D Condliffe, ...
Alzheimer's & Dementia 14 (12), 1580-1588, 2018
|Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain|
D Condliffe, A Wong, C Troakes, P Proitsi, Y Patel, L Chouliaras, ...
Neurobiology of aging 35 (8), 1850-1854, 2014
|Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder|
BPF Rutten, E Vermetten, CH Vinkers, G Ursini, NP Daskalakis, E Pishva, ...
Molecular psychiatry 23 (5), 1145-1156, 2018