Daniel Legler
Daniel Legler
Professor and Director Biotechnology Institute Thurgau at the University of Konstanz
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The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
E Oberlin, A Amara, F Bachelerie, C Bessia, JL Virelizier, AS Fernando, ...
Nature 382 (6594), 833-835, 1996
B cell–attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5
DF Legler, M Loetscher, RS Roos, I Clark-Lewis, M Baggiolini, B Moser
The Journal of experimental medicine 187 (4), 655-660, 1998
Interstitial dendritic cell guidance by haptotactic chemokine gradients
M Weber, R Hauschild, J Schwarz, C Moussion, I de Vries, DF Legler, ...
Science 339 (6117), 328-332, 2013
Recruitment of TNF receptor 1 to lipid rafts is essential for TNFα-mediated NF-κB activation
DF Legler, O Micheau, MA Doucey, J Tschopp, C Bron
Immunity 18 (5), 655-664, 2003
The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7
K Willimann, DF Legler, M Loetscher, R Stuber Roos, M Belen Delgado, ...
European journal of immunology 28 (6), 2025-2034, 1998
CARMA1 is a critical lipid raft–associated regulator of TCR-induced NF-κB activation
O Gaide, B Favier, DF Legler, D Bonnet, B Brissoni, S Valitutti, C Bron, ...
Nature immunology 3 (9), 836-843, 2002
Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells
K Schumann, T Lämmermann, M Bruckner, DF Legler, J Polleux, JP Spatz, ...
Immunity 32 (5), 703-713, 2010
Prostaglandin E 2 at new glance: novel insights in functional diversity offer therapeutic chances
DF Legler, M Bruckner, E Uetz-von Allmen, P Krause
The international journal of biochemistry & cell biology 42 (2), 198-201, 2010
CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2
E Scandella, Y Men, DF Legler, S Gillessen, L Prikler, B Ludewig, ...
Blood 103 (5), 1595-1601, 2004
Prostaglandin E2 is generally required for human dendritic cell migration and exerts its effect via EP2 and EP4 receptors
DF Legler, P Krause, E Scandella, E Singer, M Groettrup
The Journal of Immunology 176 (2), 966-973, 2006
Identification of CCR8, the receptor for the human CC chemokine I-309
RS Roos, M Loetscher, DF Legler, I Clark-Lewis, M Baggiolini, B Moser
Journal of Biological Chemistry 272 (28), 17251-17254, 1997
PrPc capping in T cells promotes its association with the lipid raft proteins reggie-1 and reggie-2 and leads to signal transduction:[Langfassung]
C Stürmer, MF Langhorst, MF Wiechers, DF Legler, ...
The FASEB journal 18 (14), 1731-1733, 2004
Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon
S Lukasiak, C Schiller, P Oehlschläger, G Schmidtke, P Krause, DF Legler, ...
Oncogene 27 (46), 6068-6074, 2008
Common and biased signaling pathways of the chemokine receptor CCR7 elicited by its ligands CCL19 and CCL21 in leukocytes
MA Hauser, DF Legler
Journal of leukocyte biology 99 (6), 869-882, 2016
Changing responsiveness to chemokines allows medullary plasmablasts to leave lymph nodes
N Wehrli, DF Legler, D Finke, KM Toellner, P Loetscher, M Baggiolini, ...
European journal of immunology 31 (2), 609-616, 2001
Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation
C Otero, M Groettrup, DF Legler
The Journal of Immunology 177 (4), 2314-2323, 2006
Superactivation of integrin (α) v (β) 3 by low antagonist concentrations
DF Legler, G Wiedle, FP Ross, BA Imhof
Journal of cell science 114 (8), 1545-1553, 2001
Differential insertion of GPI-anchored GFPs into lipid rafts of live cells
DF Legler, MA Doucey, P Schneider, L Chapatte, FC Bender, C Bron
The FASEB journal 19 (1), 73-75, 2005
Prostaglandin E2 enhances T-cell proliferation by inducing the costimulatory molecules OX40L, CD70, and 4-1BBL on dendritic cells
P Krause, M Bruckner, C Uermösi, E Singer, M Groettrup, DF Legler
Blood, The Journal of the American Society of Hematology 113 (11), 2451-2460, 2009
TYMSTR, a putative chemokine receptor selectively expressed in activated T cells, exhibits HIV-1 coreceptor function
M Loetscher, A Amara, E Oberlin, N Brass, DF Legler, P Loetscher, ...
Current Biology 7 (9), 652-660, 1997
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