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Frank Eckerdt
Frank Eckerdt
Dirección de correo verificada de northwestern.edu
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Polo-like kinases and oncogenesis
F Eckerdt, J Yuan, K Strebhardt
Oncogene 24 (2), 267-276, 2005
4792005
Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells
J Yuan, R Yan, A Krämer, F Eckerdt, M Roller, M Kaufmann, K Strebhardt
Oncogene 23 (34), 5843-5852, 2004
2452004
Cooperative phosphorylation including the activity of polo-like kinase 1 regulates the subcellular localization of cyclin B1
J Yuan, F Eckerdt, J Bereiter-Hahn, E Kurunci-Csacsko, M Kaufmann, ...
Oncogene 21 (54), 8282-8292, 2002
1612002
Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells
F Eckerdt, J Yuan, K Saxena, B Martin, S Kappel, C Lindenau, A Kramer, ...
Journal of Biological Chemistry 280 (44), 36575-36583, 2005
1512005
Targeting BET bromodomain proteins in solid tumors
V Sahai, AJ Redig, KA Collier, FD Eckerdt, HG Munshi
Oncotarget 7 (33), 53997, 2016
1042016
Polo-like kinase 1: Target and regulator of anaphase-promoting complex/cyclosome–dependent proteolysis
F Eckerdt, K Strebhardt
Cancer research 66 (14), 6895-6898, 2006
1042006
Spindle pole regulation by a discrete Eg5-interacting domain in TPX2
F Eckerdt, PA Eyers, AL Lewellyn, C Prigent, JL Maller
Current Biology 18 (7), 519-525, 2008
832008
Efficient internalization of the polo-box of polo-like kinase 1 fused to an Antennapedia peptide results in inhibition of cancer cell proliferation
J Yuan, A Krämer, F Eckerdt, M Kaufmann, K Strebhardt
Cancer research 62 (15), 4186-4190, 2002
782002
Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes
G Pascreau, F Eckerdt, AL Lewellyn, C Prigent, JL Maller
Journal of biological chemistry 284 (9), 5497-5505, 2009
732009
Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma
AD Arslan, A Sassano, D Saleiro, P Lisowski, EM Kosciuczuk, M Fischietti, ...
Oncogene 36 (43), 6006-6019, 2017
592017
Differential regulation of ZEB1 and EMT by MAPK-interacting protein kinases (MNK) and eIF4E in pancreatic cancer
K Kumar, CR Chow, K Ebine, AD Arslan, B Kwok, DJ Bentrem, FD Eckerdt, ...
Molecular cancer research 14 (2), 216-227, 2016
482016
Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo
EM Kosciuczuk, D Saleiro, B Kroczynska, EM Beauchamp, F Eckerdt, ...
Blood, The Journal of the American Society of Hematology 128 (3), 410-414, 2016
472016
Identification of a polo-like kinase 4-dependent pathway for de novo centriole formation
F Eckerdt, TM Yamamoto, AL Lewellyn, JL Maller
Current biology 21 (5), 428-432, 2011
472011
Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A
F Eckerdt, G Pascreau, M Phistry, AL Lewellyn, AA DePaoli-Roach, ...
Cell cycle 8 (15), 2413-2419, 2009
442009
MNK inhibition disrupts mesenchymal glioma stem cells and prolongs survival in a mouse model of glioblastoma
JB Bell, FD Eckerdt, K Alley, LP Magnusson, H Hussain, Y Bi, AD Arslan, ...
Molecular Cancer Research 14 (10), 984-993, 2016
432016
Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells
F Eckerdt, E Beauchamp, J Bell, A Iqbal, B Su, R Fukunaga, RR Lulla, ...
Oncotarget 5 (18), 8442, 2014
422014
Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding
G Pascreau, F Eckerdt, MEA Churchill, JL Maller
Proceedings of the National Academy of Sciences 107 (7), 2932-2937, 2010
392010
Pituitary tumor-transforming gene expression is a prognostic marker for tumor recurrence in squamous cell carcinoma of the head and neck
C Solbach, M Roller, F Eckerdt, S Peters, R Knecht
BMC cancer 6, 1-8, 2006
392006
HDL nanoparticles targeting sonic hedgehog subtype medulloblastoma
JB Bell, JS Rink, F Eckerdt, J Clymer, S Goldman, CS Thaxton, ...
Scientific reports 8 (1), 1211, 2018
342018
Differential response of glioma stem cells to arsenic trioxide therapy is regulated by MNK1 and mRNA translation
JB Bell, F Eckerdt, HD Dhruv, D Finlay, S Peng, S Kim, B Kroczynska, ...
Molecular Cancer Research 16 (1), 32-46, 2018
322018
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Artículos 1–20