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Pradeep Natarajan
Pradeep Natarajan
Massachusetts General Hospital, Harvard Medical School, Broad Institute of Harvard and MIT
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Analysis of protein-coding genetic variation in 60,706 humans
M Lek, KJ Karczewski, EV Minikel, KE Samocha, E Banks, T Fennell, ...
Nature 536 (7616), 285-291, 2016
101122016
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
AV Khera, M Chaffin, KG Aragam, ME Haas, C Roselli, SH Choi, ...
Nature genetics 50 (9), 1219-1224, 2018
24472018
Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease
S Jaiswal, P Natarajan, AJ Silver, CJ Gibson, AG Bick, E Shvartz, ...
New England Journal of Medicine 377 (2), 111-121, 2017
19912017
Genetic risk, adherence to a healthy lifestyle, and coronary disease
AV Khera, CA Emdin, I Drake, P Natarajan, AG Bick, NR Cook, ...
New England Journal of Medicine 375 (24), 2349-2358, 2016
12952016
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
D Taliun, DN Harris, MD Kessler, J Carlson, ZA Szpiech, R Torres, ...
Nature 590 (7845), 290-299, 2021
12812021
Diagnostic yield and clinical utility of sequencing familial hypercholesterolemia genes in patients with severe hypercholesterolemia
AV Khera, HH Won, GM Peloso, KS Lawson, TM Bartz, X Deng, ...
Journal of the American College of Cardiology 67 (22), 2578-2589, 2016
8972016
Genetics of blood lipids among~ 300,000 multi-ethnic participants of the Million Veteran Program
D Klarin, SM Damrauer, K Cho, YV Sun, TM Teslovich, J Honerlaw, ...
Nature genetics 50 (11), 1514-1523, 2018
5522018
Polygenic risk score identifies subgroup with higher burden of atherosclerosis and greater relative benefit from statin therapy in the primary prevention setting
P Natarajan, R Young, NO Stitziel, S Padmanabhan, U Baber, R Mehran, ...
Circulation 135 (22), 2091-2101, 2017
4942017
Inactivating Mutations in NPC1L1 and Protection from Coronary Heart Disease
Myocardial Infarction Genetics Consortium Investigators
New England Journal of Medicine 371 (22), 2072-2082, 2014
4602014
Inherited causes of clonal haematopoiesis in 97,691 whole genomes
AG Bick, JS Weinstock, SK Nandakumar, CP Fulco, EL Bao, SM Zekavat, ...
Nature 586 (7831), 763-768, 2020
4282020
ANGPTL3 deficiency and protection against coronary artery disease
NO Stitziel, AV Khera, X Wang, AJ Bierhals, AC Vourakis, AE Sperry, ...
Journal of the American College of Cardiology 69 (16), 2054-2063, 2017
4222017
Genetic association of waist-to-hip ratio with cardiometabolic traits, type 2 diabetes, and coronary heart disease
CA Emdin, AV Khera, P Natarajan, D Klarin, SM Zekavat, AJ Hsiao, ...
Jama 317 (6), 626-634, 2017
3842017
Lipoprotein (a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement
F Kronenberg, S Mora, ESG Stroes, BA Ference, BJ Arsenault, L Berglund, ...
European heart journal 43 (39), 3925-3946, 2022
3792022
The power of genetic diversity in genome-wide association studies of lipids
SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ...
Nature 600 (7890), 675-679, 2021
3792021
High-density lipoprotein and coronary heart disease: current and future therapies
P Natarajan, KK Ray, CP Cannon
Journal of the American College of Cardiology 55 (13), 1283-1299, 2010
3172010
Association of premature natural and surgical menopause with incident cardiovascular disease
MC Honigberg, SM Zekavat, K Aragam, P Finneran, D Klarin, DL Bhatt, ...
Jama 322 (24), 2411-2421, 2019
3102019
Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity
D Saleheen, P Natarajan, IM Armean, W Zhao, A Rasheed, SA Khetarpal, ...
Nature 544 (7649), 235-239, 2017
3042017
Genetic interleukin 6 signaling deficiency attenuates cardiovascular risk in clonal hematopoiesis
AG Bick, JP Pirruccello, GK Griffin, N Gupta, S Gabriel, D Saleheen, ...
Circulation 141 (2), 124-131, 2020
2942020
A statistical framework for cross-tissue transcriptome-wide association analysis
Y Hu, M Li, Q Lu, H Weng, J Wang, SM Zekavat, Z Yu, B Li, J Gu, ...
Nature genetics 51 (3), 568-576, 2019
2622019
Whole-genome sequencing to characterize monogenic and polygenic contributions in patients hospitalized with early-onset myocardial infarction
AV Khera, M Chaffin, SM Zekavat, RL Collins, C Roselli, P Natarajan, ...
Circulation 139 (13), 1593-1602, 2019
2362019
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Artículos 1–20