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Piotr Chmielarz
Piotr Chmielarz
Maj Institute of Pharmacology, PAS
Dirección de correo verificada de helsinki.fi
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Interplay between MicroRNAs and oxidative stress in neurodegenerative diseases
J Konovalova, D Gerasymchuk, I Parkkinen, P Chmielarz, A Domanskyi
International journal of molecular sciences 20 (23), 6055, 2019
1672019
Neuroprotective effects of pomegranate juice against Parkinson’s disease and presence of ellagitannins-derived metabolite—urolithin A—in the brain
M Kujawska, M Jourdes, M Kurpik, M Szulc, H Szaefer, P Chmielarz, ...
International journal of molecular sciences 21 (1), 202, 2019
1272019
Dicer and microRNAs protect adult dopamine neurons
P Chmielarz, J Konovalova, SS Najam, H Alter, TP Piepponen, H Erfle, ...
Cell death & disease 8 (5), e2813-e2813, 2017
992017
Neurotrophic factors for disease-modifying treatments of Parkinson's disease: gaps between basic science and clinical studies
P Chmielarz, M Saarma
Pharmacological Reports 72, 1195-1217, 2020
592020
Back and to the future: from neurotoxin‐induced to human Parkinson's disease models
M Airavaara, I Parkkinen, J Konovalova, K Albert, P Chmielarz, ...
Current Protocols in Neuroscience 91 (1), e88, 2020
512020
Novel multi-target azinesulfonamides of cyclic amine derivatives as potential antipsychotics with pro-social and pro-cognitive effects
P Zajdel, T Kos, K Marciniec, G Satała, V Canale, K Kamiński, M Hołuj, ...
European Journal of Medicinal Chemistry 145, 790-804, 2018
462018
GDNF/RET signaling pathway activation eliminates Lewy body pathology in midbrain dopamine neurons
P Chmielarz, Ş Er, J Konovalova, L Bandres, I Hlushchuk, K Albert, ...
Movement Disorders 35 (12), 2279-2289, 2020
442020
Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo
K Albert, DP Raymundo, A Panhelainen, A Eesmaa, L Shvachiy, ...
Molecular Therapy 29 (9), 2821-2840, 2021
322021
Inactivation of glucocorticoid receptor in noradrenergic system influences anxiety-and depressive-like behavior in mice
P Chmielarz, J Kuśmierczyk, R Parlato, G Schütz, I Nalepa, G Kreiner
PLoS One 8 (8), e72632, 2013
312013
MANF ablation causes prolonged activation of the UPR without neurodegeneration in the mouse midbrain dopamine system
E Pakarinen, T Danilova, V Võikar, P Chmielarz, P Piepponen, ...
ENeuro 7 (1), 2020
282020
Acute and repeated treatment with the 5-HT7 receptor antagonist SB 269970 induces functional desensitization of 5-HT7 receptors in rat hippocampus
K Tokarski, A Zelek-Molik, B Duszyńska, G Satała, B Bobula, M Kusek, ...
Pharmacological Reports 64 (2), 256-265, 2012
272012
Gender differences in genetic mouse models evaluated for depressive-like and antidepressant behavior
G Kreiner, P Chmielarz, A Roman, I Nalepa
Pharmacological Reports 65 (6), 1580-1590, 2013
262013
Studying pre-formed fibril induced α-synuclein accumulation in primary embryonic mouse midbrain dopamine neurons
S Er, I Hlushchuk, M Airavaara, P Chmielarz, A Domanskyi
JoVE (Journal of Visualized Experiments), e61118, 2020
252020
Functionally distinctive Ptch receptors establish multimodal Hedgehog signaling in the tooth epithelial stem cell niche
M Binder, P Chmielarz, PJ Mckinnon, LC Biggs, I Thesleff, A Balic
Stem Cells 37 (9), 1238-1248, 2019
252019
Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism
G Kreiner, K Rafa-Zabłocka, J Barut, P Chmielarz, M Kot, M Bagińska, ...
Scientific reports 9 (1), 5262, 2019
252019
Disruption of glucocorticoid receptors in the noradrenergic system leads to BDNF up-regulation and altered serotonergic transmission associated with a depressive-like phenotype …
P Chmielarz, G Kreiner, M Kot, A Zelek-Molik, M Kowalska, M Bagińska, ...
Pharmacology Biochemistry and Behavior 137, 69-77, 2015
152015
Depressive-like immobility behavior and genotype× stress interactions in male mice of selected strains
P Chmielarz, G Kreiner, J Kuśmierczyk, M Kowalska, A Roman, K Tota, ...
Stress 19 (2), 206-213, 2016
122016
Selective ablation of glucocorticoid receptors in the noradrenergic system affects evening corticosterone levels in a sex-dependent manner
P Chmielarz, G Kreiner, I Nalepa
Pharmacological Reports 67 (6), 1201-1203, 2015
112015
Alpha-synuclein preformed fibrils: a tool to understand Parkinson’s disease and develop disease modifying therapy
P Chmielarz, A Domanskyi
Neural regeneration research 16 (11), 2219-2221, 2021
82021
Chronic restraint stress induces changes in the cerebral Galpha 12/13 and Rho-GTPase signaling network
K Rafa-Zabłocka, A Zelek-Molik, B Tepper, P Chmielarz, G Kreiner, ...
Pharmacological Reports 73 (4), 1179-1187, 2021
52021
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Artículos 1–20