The role of TP53 in acute myeloid leukemia: challenges and opportunities K Barbosa, S Li, PD Adams, AJ Deshpande Genes, Chromosomes and Cancer 58 (12), 875-888, 2019 | 107 | 2019 |
A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing S Sinha, K Barbosa, K Cheng, MDM Leiserson, P Jain, A Deshpande, ... Nature communications 12 (1), 6512, 2021 | 39 | 2021 |
HIV-1 antisense protein of different clades induces autophagy and associates with the autophagy factor p62 Z Liu, C Torresilla, Y Xiao, PT Nguyen, C Caté, K Barbosa, É Rassart, ... Journal of virology 93 (2), 10.1128/jvi. 01757-18, 2019 | 27 | 2019 |
Acute myeloid leukemia driven by the CALM-AF10 fusion gene is dependent on BMI1 K Barbosa, A Deshpande, BR Chen, A Ghosh, Y Sun, S Dutta, M Weetall, ... Experimental hematology 74, 42-51. e3, 2019 | 18 | 2019 |
A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML BR Chen, A Deshpande, K Barbosa, M Kleppe, X Lei, N Yeddula, PS Vela, ... Blood, The Journal of the American Society of Hematology 137 (24), 3403-3415, 2021 | 14 | 2021 |
The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations BJ Klein, A Deshpande, KL Cox, F Xuan, M Zandian, K Barbosa, S Khanal, ... Nature communications 12 (1), 4130, 2021 | 10 | 2021 |
The role of DOT1L in normal and malignant hematopoiesis O Arnold, K Barbosa, AJ Deshpande, N Zhu Frontiers in Cell and Developmental Biology 10, 917125, 2022 | 7 | 2022 |
Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells D Raveendra-Panickar, D Finlay, FI Layng, LJ Lambert, M Celeridad, ... Journal of Biological Chemistry 298 (1), 2022 | 6 | 2022 |
Integrated computational and experimental identification of p53, KRAS and VHL mutant selection associated with CRISPR-Cas9 editing S Sinha, KB Guerra, K Cheng, MDM Leiserson, DM Wilson III, BM Ryan, ... bioRxiv, 407767, 2018 | 4 | 2018 |
High-Density Domain-Focused CRISPR Screens Reveal Epigenetic Regulators of Hox/Meis Gene Expression in Acute Myeloid Leukemia K Barbosa, A Deshpande, P Xiang, BR Chen, A Brown, N Robertson, ... Blood 136, 2-3, 2020 | 3 | 2020 |
Transcriptional control of leukemogenesis by the chromatin reader SGF29 K Barbosa, A Deshpande, M Perales, P Xiang, R Murad, AB Pramod, ... Blood 143 (8), 697-712, 2024 | 2 | 2024 |
Author Correction: A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing S Sinha, K Barbosa, K Cheng, MDM Leiserson, P Jain, A Deshpande, ... Nature Communications 13, 2022 | 2 | 2022 |
A systematic genome-wide mapping of the oncogenic risks associated with CRISPR-Cas9 editing S Sinha, K Cheng, MD Leiserson, DM Wilson, BM Ryan, JS Lee, ... bioRxiv 407767, 2018 | 2 | 2018 |
Therapeutic targeting of leukemia stem cells in acute myeloid leukemia K Barbosa, AJ Deshpande Frontiers in Oncology 13, 2023 | | 2023 |
High Density Domain-Focused CRISPR Screens Reveal Novel Epigenetic Regulators ofHOX/MEISActivation in Acute Myeloid Leukemia K Barbosa, A Deshpande, M Perales, P Xiang, R Murad, A Minkina, ... | | 2022 |
High Density Domain-Focused CRISPR Screens Reveal Novel Epigenetic Regulators of HOX/MEIS Activation in Acute Myeloid Leukemia K Barbosa, A Deshpande, M Perales, P Xiang, R Murad, A Minkina, ... bioRxiv, 2022.12. 12.519332, 2022 | | 2022 |
Abstract PR004: High-density CRISPR screens reveal mechanisms of chromatin regulation of stemness networks in acute myeloid leukemia KOB Guerra, A Deshpande, P Xiang, A Minkina, F Schischlik, A Brown, ... Cancer Research 82 (23_Supplement_2), PR004-PR004, 2022 | | 2022 |
3030–THE EPIGENETIC REGULATOR LANDSCAPE OF STEMNESS NETWORKS IN ACUTE MYELOID LEUKEMIA K Barbosa, A Deshpande, P Xiang, A Minkina, F Schischlik, A Brown, ... Experimental Hematology 111, S59-S60, 2022 | | 2022 |
A Synthetic Lethal Approach to Eradicate AML Via Synergistic Activation of Pro-Apoptotic p53 By MDM2 and BET Inhibitors S Li, AL Latif, A Newcombe, K Gilrory, N Robertson, X Lei, D Finlay, ... Blood 136, 14, 2020 | | 2020 |
A synthetic lethality approach to eradicate AML via synergistic activation of pro-apoptotic p53 by MDM2 and BET inhibitors S Li, AL Latif, A Newcombe, K Gilrory, N Robertson, D Finlay, X Lei, ... EXPERIMENTAL HEMATOLOGY 88, S70-S70, 2020 | | 2020 |