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Simeone Marino
Simeone Marino
University of Michigan Medical School
Dirección de correo verificada de umich.edu - Página principal
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A methodology for performing global uncertainty and sensitivity analysis in systems biology
S Marino, IB Hogue, CJ Ray, DE Kirschner
Journal of theoretical biology 254 (1), 178-196, 2008
25542008
Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms
JT Mattila, OO Ojo, D Kepka-Lenhart, S Marino, JH Kim, SY Eum, LE Via, ...
The Journal of Immunology 191 (2), 773-784, 2013
3632013
Variability in tuberculosis granuloma T cell responses exists, but a balance of pro-and anti-inflammatory cytokines is associated with sterilization
HP Gideon, JY Phuah, AJ Myers, BD Bryson, MA Rodgers, MT Coleman, ...
PLoS pathogens 11 (1), e1004603, 2015
3152015
The human immune response to Mycobacterium tuberculosis in lung and lymph node
S Marino, DE Kirschner
Journal of theoretical biology 227 (4), 463-486, 2004
2172004
Dynamic balance of pro‐and anti‐inflammatory signals controls disease and limits pathology
JM Cicchese, S Evans, C Hult, LR Joslyn, T Wessler, JA Millar, S Marino, ...
Immunological reviews 285 (1), 147-167, 2018
2132018
Mathematical modeling of primary succession of murine intestinal microbiota
S Marino, NT Baxter, GB Huffnagle, JF Petrosino, PD Schloss
Proceedings of the National Academy of Sciences 111 (1), 439-444, 2014
2132014
Tumor necrosis factor blockade in chronic murine tuberculosis enhances granulomatous inflammation and disorganizes granulomas in the lungs
SD Chakravarty, G Zhu, MC Tsai, VP Mohan, S Marino, DE Kirschner, ...
Infection and immunity 76 (3), 916-926, 2008
1972008
Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection
S Marino, NA Cilfone, JT Mattila, JJ Linderman, JAL Flynn, DE Kirschner
Infection and immunity 83 (1), 324-338, 2015
1952015
Multiscale computational modeling reveals a critical role for TNF-α receptor 1 dynamics in tuberculosis granuloma formation
M Fallahi-Sichani, M El-Kebir, S Marino, DE Kirschner, JJ Linderman
The Journal of Immunology 186 (6), 3472-3483, 2011
1942011
Dendritic cell trafficking and antigen presentation in the human immune response to Mycobacterium tuberculosis
S Marino, S Pawar, CL Fuller, TA Reinhart, JAL Flynn, DE Kirschner
The Journal of Immunology 173 (1), 494-506, 2004
1932004
Intracellular Bacillary Burden Reflects a Burst Size for Mycobacterium tuberculosis In Vivo
T Repasy, J Lee, S Marino, N Martinez, DE Kirschner, G Hendricks, ...
PLoS pathogens 9 (2), e1003190, 2013
1412013
TNF and IL-10 are major factors in modulation of the phagocytic cell environment in lung and lymph node in tuberculosis: a next-generation two-compartmental model
S Marino, A Myers, JAL Flynn, DE Kirschner
Journal of theoretical biology 265 (4), 586-598, 2010
1112010
Differences in reactivation of tuberculosis induced from anti-TNF treatments are based on bioavailability in granulomatous tissue
S Marino, D Sud, H Plessner, PL Lin, J Chan, JAL Flynn, DE Kirschner
PLoS computational biology 3 (10), e194, 2007
1112007
A hybrid multi-compartment model of granuloma formation and T cell priming in tuberculosis
S Marino, M El-Kebir, D Kirschner
Journal of theoretical biology 280 (1), 50-62, 2011
992011
Regulation of glycolysis in Lactococcus lactis: an unfinished systems biological case study
EO Voit, J Almeida, S Marino, R Lall, G Goel, AR Neves, H Santos
IEE Proceedings-Systems Biology 153 (4), 286-298, 2006
962006
Data-parallel algorithms for agent-based model simulation of tuberculosis on graphics processing units.
RM D'Souza, M Lysenko, S Marino, DE Kirschner
SpringSim, 2009
812009
Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity–mediated antimicrobial responses with caseation during Mycobacterium …
NA Cilfone, CB Ford, S Marino, JT Mattila, HP Gideon, JAL Flynn, ...
The Journal of Immunology 194 (2), 664-677, 2015
722015
A review of computational and mathematical modeling contributions to our understanding of Mycobacterium tuberculosis within-host infection and treatment
D Kirschner, E Pienaar, S Marino, JJ Linderman
Current opinion in systems biology 3, 170-185, 2017
692017
Understanding the immune response in tuberculosis using different mathematical models and biological scales
D Gammack, S Ganguli, S Marino, J Segovia-Juarez, DE Kirschner
Multiscale Modeling & Simulation 3 (2), 312-345, 2005
682005
Characterizing the dynamics of CD4+ T cell priming within a lymph node
JJ Linderman, T Riggs, M Pande, M Miller, S Marino, DE Kirschner
The Journal of Immunology 184 (6), 2873-2885, 2010
672010
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Artículos 1–20