Douglas Lauffenburger
Douglas Lauffenburger
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Cell migration: a physically integrated molecular process
DA Lauffenburger, AF Horwitz
cell 84 (3), 359-369, 1996
Causal protein-signaling networks derived from multiparameter single-cell data
K Sachs, O Perez, D Pe'er, DA Lauffenburger, GP Nolan
Science 308 (5721), 523-529, 2005
Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness
SP Palecek, JC Loftus, MH Ginsberg, DA Lauffenburger, AF Horwitz
Nature 385 (6616), 537-540, 1997
Receptors: models for binding, trafficking, and signaling
DA Lauffenburger, J Linderman
Oxford University Press, 1996
Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis
MH Zaman, LM Trapani, AL Sieminski, D MacKellar, H Gong, RD Kamm, ...
Proceedings of the National Academy of Sciences 103 (29), 10889-10894, 2006
Cell adhesion and motility depend on nanoscale RGD clustering
G Maheshwari, G Brown, DA Lauffenburger, A Wells, LG Griffith
Journal of cell science 113 (10), 1677-1686, 2000
Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength
PA DiMilla, JA Stone, JA Quinn, SM Albelda, DA Lauffenburger
The Journal of cell biology 122 (3), 729-737, 1993
Mathematical model for the effects of adhesion and mechanics on cell migration speed
PA DiMilla, K Barbee, DA Lauffenburger
Biophysical journal 60 (1), 15-37, 1991
Physicochemical modelling of cell signalling pathways
BB Aldridge, JM Burke, DA Lauffenburger, PK Sorger
Nature cell biology 8 (11), 1195-1203, 2006
Vector unpacking as a potential barrier for receptor‐mediated polyplex gene delivery
DV Schaffer, NA Fidelman, N Dan, DA Lauffenburger
Biotechnology and bioengineering 67 (5), 598-606, 2000
A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis
KA Janes, JG Albeck, S Gaudet, PK Sorger, DA Lauffenburger, MB Yaffe
Science 310 (5754), 1646-1653, 2005
Time-resolved Mass Spectrometry of Tyrosine Phosphorylation Sites in the Epidermal Growth Factor Receptor Signaling Network Reveals Dynamic Modules* S
Y Zhang, A Wolf-Yadlin, PL Ross, DJ Pappin, J Rush, DA Lauffenburger, ...
Molecular & Cellular Proteomics 4 (9), 1240-1250, 2005
Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks
A Wolf-Yadlin, S Hautaniemi, DA Lauffenburger, FM White
Proceedings of the National Academy of Sciences 104 (14), 5860-5865, 2007
Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus
LY Koo, DJ Irvine, AM Mayes, DA Lauffenburger, LG Griffith
Journal of cell science 115 (7), 1423-1433, 2002
Microfluidic shear devices for quantitative analysis of cell adhesion
H Lu, LY Koo, WM Wang, DA Lauffenburger, LG Griffith, KF Jensen
Analytical chemistry 76 (18), 5257-5264, 2004
Regulation of cell migration by the calcium-dependent protease calpain
A Huttenlocher, SP Palecek, Q Lu, W Zhang, RL Mellgren, ...
Journal of Biological Chemistry 272 (52), 32719-32722, 1997
Cutting to the chase: calpain proteases in cell motility
A Glading, DA Lauffenburger, A Wells
Trends in cell biology 12 (1), 46-54, 2002
Biological surface engineering: a simple system for cell pattern formation
S Zhang, L Yan, M Altman, M Lässle, H Nugent, F Frankel, ...
Biomaterials 20 (13), 1213-1220, 1999
A functional role for antibodies in tuberculosis
LL Lu, AW Chung, TR Rosebrock, M Ghebremichael, WH Yu, PS Grace, ...
Cell 167 (2), 433-443. e14, 2016
Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data
WW Chen, B Schoeberl, PJ Jasper, M Niepel, UB Nielsen, ...
Molecular systems biology 5 (1), 239, 2009
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