| Break-induced replication repair of damaged forks induces genomic duplications in human cells L Costantino, SK Sotiriou, JK Rantala, S Magin, E Mladenov, T Helleday, ... Science 343 (6166), 88-91, 2014 | 504 | 2014 |
| FZD4 as a Mediator of ERG Oncogene–Induced WNT Signaling and Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells S Gupta, K Iljin, H Sara, JP Mpindi, T Mirtti, P Vainio, J Rantala, K Alanen, ... Cancer research 70 (17), 6735-6745, 2010 | 318 | 2010 |
| SHARPIN is an endogenous inhibitor of β1-integrin activation JK Rantala, J Pouwels, T Pellinen, S Veltel, P Laasola, E Mattila, ... Nature cell biology 13 (11), 1315-1324, 2011 | 247 | 2011 |
| Integrin trafficking regulated by Rab21 is necessary for cytokinesis T Pellinen, S Tuomi, A Arjonen, M Wolf, H Edgren, H Meyer, R Grosse, ... Developmental cell 15 (3), 371-385, 2008 | 230 | 2008 |
| Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer T Risom, EM Langer, MP Chapman, J Rantala, AJ Fields, C Boniface, ... Nature communications 9 (1), 1-17, 2018 | 174 | 2018 |
| MiR-9,-31, and-182 deregulation promote proliferation and tumor cell survival in colon cancer L Cekaite, JK Rantala, J Bruun, M Guriby, TH Ågesen, SA Danielsen, ... Neoplasia 14 (9), 868-IN21, 2012 | 171 | 2012 |
| Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion M Björkman, P Östling, V Härmä, J Virtanen, JP Mpindi, J Rantala, T Mirtti, ... Oncogene 31 (29), 3444-3456, 2012 | 135 | 2012 |
| Distinct roles of AKT isoforms in regulating β1-integrin activity, migration, and invasion in prostate cancer R Virtakoivu, T Pellinen, JK Rantala, M Perälä, J Ivaska Molecular biology of the cell 23 (17), 3357-3369, 2012 | 93 | 2012 |
| CDK‐mediated activation of the SCFFBXO28 ubiquitin ligase promotes MYC‐driven transcription and tumourigenesis and predicts poor survival in breast cancer D Cepeda, HF Ng, HR Sharifi, S Mahmoudi, VS Cerrato, E Fredlund, ... EMBO molecular medicine 5 (7), 1067-1086, 2013 | 85 | 2013 |
| Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade H Lue, J Podolak, K Kolahi, L Cheng, S Rao, D Garg, CH Xue, JK Rantala, ... Genes & Development 31 (20), 2067-2084, 2017 | 82 | 2017 |
| FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells JZ Shen, Z Qiu, Q Wu, D Finlay, G Garcia, D Sun, J Rantala, W Barshop, ... Cell 184 (2), 352-369. e23, 2021 | 80 | 2021 |
| DNA methylation and transcriptome changes associated with cisplatin resistance in ovarian cancer RJ Lund, K Huhtinen, J Salmi, J Rantala, EV Nguyen, R Moulder, ... Scientific reports 7 (1), 1469, 2017 | 80 | 2017 |
| The gene expression landscape of breast cancer is shaped by tumor protein p53 status and epithelial-mesenchymal transition E Fredlund, J Staaf, JK Rantala, O Kallioniemi, Å Borg, M Ringnér Breast cancer research 14, 1-13, 2012 | 78 | 2012 |
| A cell spot microarray method for production of high density siRNA transfection microarrays JK Rantala, R Mäkelä, AR Aaltola, P Laasola, JP Mpindi, M Nees, ... BMC genomics 12, 1-15, 2011 | 73 | 2011 |
| Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer LL Christensen, A Holm, J Rantala, O Kallioniemi, MH Rasmussen, ... PLoS One 9 (6), e96767, 2014 | 58 | 2014 |
| A functional genetic screen reveals new regulators of β1-integrin activity T Pellinen, JK Rantala, A Arjonen, JP Mpindi, O Kallioniemi, J Ivaska Journal of cell science 125 (3), 649-661, 2012 | 58 | 2012 |
| Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2 JK Rantala, H Edgren, L Lehtinen, M Wolf, K Kleivi, HKM Vollan, ... Neoplasia 12 (11), 877-IN14, 2010 | 56 | 2010 |
| Combined prognostic value of CD274 (PD-L1)/PDCDI (PD-1) expression and immune cell infiltration in colorectal cancer as per mismatch repair status M Ahtiainen, EV Wirta, T Kuopio, T Seppälä, J Rantala, JP Mecklin, ... Modern Pathology 32 (6), 866-883, 2019 | 53 | 2019 |
| Distinct c-Met activation mechanisms induce cell rounding or invasion through pathways involving integrins, RhoA and HIP1 A Mai, G Muharram, R Barrow-McGee, H Baghirov, J Rantala, ... Journal of cell science 127 (9), 1938-1952, 2014 | 50 | 2014 |
| Dual-light photodynamic therapy administered daily provides a sustained antibacterial effect on biofilm and prevents Streptococcus mutans adaptation S Nikinmaa, H Alapulli, P Auvinen, M Vaara, J Rantala, E Kankuri, ... PloS one 15 (5), e0232775, 2020 | 46 | 2020 |
