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Jia-Ren Lin
Jia-Ren Lin
Harvard Medical School; Stanford University; National Taiwan University
Dirección de correo verificada de hms.harvard.edu - Página principal
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Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ...
Science 352 (6282), 189-196, 2016
31232016
A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
7772018
Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method
JR Lin, M Fallahi-Sichani, PK Sorger
Nature communications 6 (1), 8390, 2015
3952015
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes
PKS Jia-Ren Lin, Benjamin Izar, Shu Wang, Clarence Yapp, Shaolin Mei, Parin ...
eLIFE 7, e31657, 2018
3742018
The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations
AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ...
Cell systems 6 (1), 13-24, 2018
3302018
The Human Tumor Atlas Network: charting tumor transitions across space and time at single-cell resolution
O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ...
Cell 181 (2), 236-249, 2020
2602020
Bidirectional signals transduced by DAPK–ERK interaction promote the apoptotic effect of DAPK
CH Chen, WJ Wang, JC Kuo, HC Tsai, JR Lin, ZF Chang, RH Chen
The EMBO journal 24 (2), 294-304, 2005
2602005
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de‐differentiated state
M Fallahi‐Sichani, V Becker, B Izar, GJ Baker, JR Lin, SA Boswell, P Shah, ...
Molecular systems biology 13 (1), 905, 2017
2122017
A single-cell landscape of high-grade serous ovarian cancer
B Izar, I Tirosh, EH Stover, I Wakiro, MS Cuoco, I Alter, C Rodman, ...
Nature Medicine 26 (8), 1271-1279, 2020
2012020
SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis
JR Lin, MK Zeman, JY Chen, MC Yee, KA Cimprich
Molecular cell 42 (2), 237-249, 2011
1872011
A two-dimensional ERK-AKT signaling code for an NGF-triggered cell-fate decision
JY Chen, JR Lin, KA Cimprich, T Meyer
Molecular cell 45 (2), 196-209, 2012
1392012
NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies
HJC Choi, JR Lin, JB Vannier, GG Slaats, AC Kile, RD Paulsen, ...
Molecular cell 51 (4), 423-439, 2013
1282013
Dosage of Dyrk1a Shifts Cells within a p21-Cyclin D1 Signaling Map to Control the Decision to Enter the Cell Cycle
JY Chen, JR Lin, FC Tsai, T Meyer
Molecular cell 52 (1), 87-100, 2013
1252013
Cyclic Immunofluorescence (CycIF), A Highly Multiplexed Method for Single‐cell Imaging
JR Lin, M Fallahi‐Sichani, JY Chen, PK Sorger
Current protocols in chemical biology 8 (4), 251-264, 2016
1122016
Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase
JC Kuo, JR Lin, JM Staddon, H Hosoya, RH Chen
Journal of cell science 116 (23), 4777-4790, 2003
942003
Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer
AK Mehta, EM Cheney, CA Hartl, C Pantelidou, M Oliwa, JA Castrillon, ...
Nature Cancer 2 (1), 66-82, 2021
892021
Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging.
Z Du, JR Lin, R Rashid, Z Maliga, S Wang, JC Aster, B Izar, PK Sorger, ...
Nature protocols 14 (10), 2900-2930, 2019
682019
MCMICRO: A scalable, modular image-processing pipeline for multiplexed tissue imaging
D Schapiro, A Sokolov, C Yapp, YA Chen, JL Muhlich, J Hess, ...
Nature methods 19 (3), 311-315, 2022
592022
Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma
S Coy, R Rashid, JR Lin, Z Du, AM Donson, TC Hankinson, NK Foreman, ...
Neuro-oncology 20 (8), 1101-1112, 2018
592018
Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade
IF Dunn, Z Du, M Touat, MB Sisti, PY Wen, R Umeton, AM Dubuc, ...
JCO precision oncology 2, 2018
442018
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Artículos 1–20