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Cyrus Ghajar
Cyrus Ghajar
Dirección de correo verificada de fredhutch.org
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Tumour exosome integrins determine organotropic metastasis
A Hoshino, B Costa-Silva, TL Shen, G Rodrigues, A Hashimoto, ...
Nature 527 (7578), 329-335, 2015
45092015
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
H Peinado, M Alečković, S Lavotshkin, I Matei, B Costa-Silva, ...
Nature medicine 18 (6), 883-891, 2012
38552012
Pre-metastatic niches: organ-specific homes for metastases
H Peinado, H Zhang, IR Matei, B Costa-Silva, A Hoshino, G Rodrigues, ...
Nature Reviews Cancer 17 (5), 302-317, 2017
16032017
The perivascular niche regulates breast tumour dormancy
CM Ghajar, H Peinado, H Mori, IR Matei, KJ Evason, H Brazier, D Almeida, ...
Nature cell biology 15 (7), 807-817, 2013
11132013
Extracellular vesicle and particle biomarkers define multiple human cancers
A Hoshino, HS Kim, L Bojmar, KE Gyan, M Cioffi, J Hernandez, ...
Cell 182 (4), 1044-1061. e18, 2020
8082020
Prevascularization of a fibrin-based tissue construct accelerates the formation of functional anastomosis with host vasculature
X Chen, AS Aledia, CM Ghajar, CK Griffith, AJ Putnam, CCW Hughes, ...
Tissue Engineering Part A 15 (6), 1363-1371, 2009
4022009
The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer
B Weigelt, CM Ghajar, MJ Bissell
Advanced drug delivery reviews 69, 42-51, 2014
3962014
The effect of matrix density on the regulation of 3-D capillary morphogenesis
CM Ghajar, X Chen, JW Harris, V Suresh, CCW Hughes, NL Jeon, ...
Biophysical journal 94 (5), 1930-1941, 2008
3212008
Metastasis prevention by targeting the dormant niche
CM Ghajar
Nature Reviews Cancer 15 (4), 238-247, 2015
3152015
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis
G Rodrigues, A Hoshino, CM Kenific, IR Matei, L Steiner, D Freitas, ...
Nature cell biology 21 (11), 1403-1412, 2019
3082019
Mesenchymal stem cells enhance angiogenesis in mechanically viable prevascularized tissues via early matrix metalloproteinase upregulation
CM Ghajar, KS Blevins, CCW Hughes, SC George, AJ Putnam
Tissue engineering 12 (10), 2875-2888, 2006
2812006
The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system
SR Peyton, PD Kim, CM Ghajar, D Seliktar, AJ Putnam
Biomaterials 29 (17), 2597-2607, 2008
2632008
The emergence of ECM mechanics and cytoskeletal tension as important regulators of cell function
SR Peyton, CM Ghajar, CB Khatiwala, AJ Putnam
Cell biochemistry and biophysics 47, 300-320, 2007
2362007
Circulating and disseminated tumor cells: harbingers or initiators of metastasis?
A Dasgupta, AR Lim, CM Ghajar
Molecular oncology 11 (1), 40-61, 2017
2182017
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy
P Carlson, A Dasgupta, CA Grzelak, J Kim, A Barrett, IM Coleman, ...
Nature cell biology 21 (2), 238-250, 2019
2142019
Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging
CM Ghajar, MJ Bissell
Histochemistry and cell biology 130, 1105-1118, 2008
2002008
Mesenchymal cells stimulate capillary morphogenesis via distinct proteolytic mechanisms
CM Ghajar, S Kachgal, E Kniazeva, H Mori, SV Costes, SC George, ...
Experimental cell research 316 (5), 813-825, 2010
1962010
Matrix metalloproteinase control of capillary morphogenesis
CM Ghajar, SC George, A Putnam
Critical Reviews™ in Eukaryotic Gene Expression 18 (3), 2008
1512008
Dormant tumour cells, their niches and the influence of immunity
ET Goddard, I Bozic, SR Riddell, CM Ghajar
Nature cell biology 20 (11), 1240-1249, 2018
1442018
Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1
H Mori, AT Lo, JL Inman, J Alcaraz, CM Ghajar, JD Mott, CM Nelson, ...
Development 140 (2), 343-352, 2013
1252013
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Artículos 1–20