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Makoto R. Hara
Makoto R. Hara
Dirección de correo verificada de novartis.com
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S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding
MR Hara, N Agrawal, SF Kim, MB Cascio, M Fujimuro, Y Ozeki, ...
Nature cell biology 7 (7), 665-674, 2005
12282005
Distinct phosphorylation sites on the β2-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin
KN Nobles, K Xiao, S Ahn, AK Shukla, CM Lam, S Rajagopal, ...
Science signaling 4 (185), ra51-ra51, 2011
6912011
Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor
K Matsushita, CN Morrell, B Cambien, SX Yang, M Yamakuchi, C Bao, ...
Cell 115 (2), 139-150, 2003
5162003
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
MR Hara, JJ Kovacs, EJ Whalen, S Rajagopal, RT Strachan, W Grant, ...
Nature 477 (7364), 349-353, 2011
4802011
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis
N Sen, MR Hara, MD Kornberg, MB Cascio, BI Bae, N Shahani, B Thomas, ...
Nature cell biology 10 (7), 866-873, 2008
4472008
GAPDH mediates nitrosylation of nuclear proteins
MD Kornberg, N Sen, MR Hara, KR Juluri, JVK Nguyen, AM Snowman, ...
Nature cell biology 12 (11), 1094-1100, 2010
4262010
Cell signaling and neuronal death
MR Hara, SH Snyder
Annu. Rev. Pharmacol. Toxicol. 47, 117-141, 2007
2932007
Neuroprotection by pharmacologic blockade of the GAPDH death cascade
MR Hara, B Thomas, MB Cascio, BI Bae, LD Hester, VL Dawson, ...
Proceedings of the National Academy of Sciences 103 (10), 3887-3889, 2006
2802006
GAPDH as a sensor of NO stress
MR Hara, MB Cascio, A Sawa
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (5), 502-509, 2006
2622006
Arrestin development: emerging roles for β-arrestins in developmental signaling pathways
JJ Kovacs, MR Hara, CL Davenport, J Kim, RJ Lefkowitz
Developmental cell 17 (4), 443-458, 2009
2432009
Nitric oxide–GAPDH–Siah: a novel cell death cascade
MR Hara, SH Snyder
Cellular and molecular neurobiology 26, 525-536, 2006
2312006
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR)
K Xiao, J Sun, J Kim, S Rajagopal, B Zhai, J Villén, W Haas, JJ Kovacs, ...
Proceedings of the National Academy of Sciences 107 (34), 15299-15304, 2010
2252010
β-Arrestin-2 mediates anti-apoptotic signaling through regulation of BAD phosphorylation
S Ahn, J Kim, MR Hara, XR Ren, RJ Lefkowitz
Journal of Biological Chemistry 284 (13), 8855-8865, 2009
1982009
GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation
N Sen, MR Hara, AS Ahmad, MB Cascio, A Kamiya, JT Ehmsen, ...
Neuron 63 (1), 81-91, 2009
1572009
Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH
BI Bae, MR Hara, MB Cascio, CL Wellington, MR Hayden, CA Ross, ...
Proceedings of the National Academy of Sciences 103 (9), 3405-3409, 2006
1532006
Pharmacological blockade of a β2AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model
MR Hara, BD Sachs, MG Caron, RJ Lefkowitz
Cell cycle 12 (2), 219-224, 2013
962013
β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression
SK Shenoy, S Han, YL Zhao, MR Hara, T Oliver, Y Cao, MW Dewhirst
Oncogene 31 (3), 282-292, 2012
812012
βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1
A Nieto, MR Hara, V Quereda, W Grant, V Saunders, K Xiao, ...
Cell Death & Differentiation 27 (4), 1200-1213, 2020
152020
Correction: Global phosphorylation analysis of ß-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR)
K Xiao, J Sun, J Kim, S Rajagopal, B Zhai, J Villén, W Haas, JJ Kovacs, ...
Proceedings of the National Academy of Sciences of the United States of …, 2012
2012
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Artículos 1–19