| A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo Y Nunez-Figueredo, J Ramírez-Sánchez, G Hansel, ENS Pires, N Merino, ... Neuropharmacology 85, 517-527, 2014 | 52 | 2014 |
| JM-20, a novel benzodiazepine–dihydropyridine hybrid molecule, protects mitochondria and prevents ischemic insult-mediated neural cell death in vitro Y Nuñez-Figueredo, J Ramírez-Sánchez, R Delgado-Hernández, ... European journal of pharmacology 726, 57-65, 2014 | 43 | 2014 |
| Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: Mitoprotection against Ca2+-induced mitochondrial impairment Y Nunez-Figueredo, GL Pardo-Andreu, J Ramírez-Sánchez, ... Brain research bulletin 109, 68-76, 2014 | 41 | 2014 |
| Mitochondrial involvement in memory impairment induced by scopolamine in rats M Wong-Guerra, J Jiménez-Martin, GL Pardo-Andreu, ... Neurological research 39 (7), 649-659, 2017 | 39 | 2017 |
| Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway J Ramírez-Sánchez, ENS Pires, Y Nuñez-Figueredo, GL Pardo-Andreu, ... Neurochemistry international 90, 215-223, 2015 | 34 | 2015 |
| Characterization of the anxiolytic and sedative profile of JM-20: a novel benzodiazepine–dihydropyridine hybrid molecule YN Figueredo, EO Rodríguez, YV Reyes, CC Domínguez, AL Parra, ... Neurological research 35 (8), 804-812, 2013 | 29 | 2013 |
| JM-20 treatment after MCAO reduced astrocyte reactivity and neuronal death on peri-infarct regions of the rat brain J Ramírez-Sánchez, ENS Pires, A Meneghetti, G Hansel, ... Molecular Neurobiology 56, 502-512, 2019 | 25 | 2019 |
| The effects of JM-20 on the glutamatergic system in synaptic vesicles, synaptosomes and neural cells cultured from rat brain Y Nuñez-Figueredo, GLP Andreu, SO Loureiro, M Ganzella, ... Neurochemistry international 81, 41-47, 2015 | 22 | 2015 |
| JM-20 protects memory acquisition and consolidation on scopolamine model of cognitive impairment M Wong-Guerra, J Jiménez-Martin, LA Fonseca-Fonseca, ... Neurological research 41 (5), 385-398, 2019 | 17 | 2019 |
| JM-20, a novel hybrid molecule, protects against rotenone-induced neurotoxicity in experimental model of Parkinson’s disease LA Fonseca-Fonseca, M Wong-Guerra, J Ramírez-Sánchez, ... Neuroscience letters 690, 29-35, 2019 | 15 | 2019 |
| Multi-targeting effects of a new synthetic molecule (JM-20) in experimental models of cerebral ischemia Y Nuñez-Figueredo, J Ramírez-Sánchez, GLP Andreu, ... Pharmacological Reports 70 (4), 699-704, 2018 | 11 | 2018 |
| JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson’s disease: Mitochondrial protection and antioxidant properties LA Fonseca-Fonseca, VDA da Silva, M Wong-Guerra, J Ramírez-Sánchez, ... Neurotoxicology 82, 89-98, 2021 | 10 | 2021 |
| JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats M Wong-Guerra, Y Montano-Peguero, J Ramírez-Sánchez, ... Neurotoxicology 87, 70-85, 2021 | 9 | 2021 |
| KM-34, a novel antioxidant compound, protects against 6-hydroxydopamine-induced mitochondrial damage and neurotoxicity LA Fonseca-Fonseca, Y Nuñez-Figueredo, JR Sánchez, MW Guerra, ... Neurotoxicity Research 36, 279-291, 2019 | 9 | 2019 |
| Therapeutic potential of the novel hybrid molecule JM-20 against focal cortical ischemia in rats Y Verdecia-Reyes, DO Souza, YN Figueredo, J Ramírez-Sanchez, ... Journal of Pharmacy & Pharmacognosy Research 4 (4), 153-158, 2016 | 8 | 2016 |
| Neuroprotective action and free radical scavenging activity of Guttiferone-A, a naturally occurring prenylated benzophenone Y Nunez-Figueredo, L García-Pupo, J Ramírez-Sánchez, ... Arzneimittelforschung 62 (12), 583-589, 2012 | 8 | 2012 |
| Antioxidant and Neuroprotective Effects of KM-34, A Novel Synthetic Catechol, Against Oxidative Stress-Induced Neurotoxicity Y Nuñez-Figueredo, J Ramirez-Sanchez, YA Issac, E Ochoa-Rodriguez, ... Drug research 68 (05), 263-269, 2018 | 4 | 2018 |
| Semi-synthetic sapogenin exerts neuroprotective effects by skewing the brain ischemia reperfusion transcriptome towards inflammatory resolution L García-Pupo, JR Sánchez, D Ratman, C Pérez-Novo, K Declerck, ... Brain, Behavior, and Immunity 64, 103-115, 2017 | 2 | 2017 |
| Novel arylidene malonate derivative, KM-34, showed neuroprotective effects on in vitro and in vivo models of ischemia/reperfusion J Ramírez-Sánchez, M Wong-Guerra, LA Fonseca-Fonseca, ... European Journal of Pharmacology 899, 174025, 2021 | 1 | 2021 |
| Phenol compound and combination of same with a benzodiazepine fused to 1, 4-dihydropyridine for treating diseases of the central nervous and vascular systems EO Rodríguez, YV Reyes, YN FIGUEREDO, JR SÁNCHEZ, MW GUERRA, ... US Patent 10,722,491, 2020 | 1 | 2020 |
Yanier Nunez-FigueredoDrug Research and Development CenterDirección de correo verificada de cidem.cu
