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Brigitte van Zundert
Brigitte van Zundert
Full Professor
Dirección de correo verificada de unab.cl - Página principal
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Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons
K Castillo, M Nassif, V Valenzuela, F Rojas, S Matus, G Mercado, ...
Autophagy 9 (9), 1308-1320, 2013
3492013
Receptor compartmentalization and trafficking at glutamate synapses: a developmental proposal
B van Zundert, A Yoshii, M Constantine-Paton
Trends in neurosciences 27 (7), 428-437, 2004
3262004
Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis
B van Zundert, MH Peuscher, M Hynynen, A Chen, RL Neve, RH Brown Jr, ...
The Journal of Neuroscience 28 (43), 10864-10874, 2008
2642008
Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer’s disease mice
FJ Bustos, E Ampuero, N Jury, R Aguilar, F Falahi, J Toledo, J Ahumada, ...
Brain 140 (12), 3252-3268, 2017
1422017
Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress
F Rojas, N Cortes, S Abarzua, A Dyrda, B van Zundert
Frontiers in cellular neuroscience 8, 24, 2014
1312014
Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability
E Fritz, P Izaurieta, A Weiss, FR Mir, P Rojas, D Gonzalez, F Rojas, ...
Journal of neurophysiology 109 (11), 2803-2814, 2013
1282013
ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers
D Gonzalez, O Contreras, DL Rebolledo, JP Espinoza, B Van Zundert, ...
PLoS One 12 (5), e0177649, 2017
1182017
ALS‐linked protein disulfide isomerase variants cause motor dysfunction
U Woehlbier, A Colombo, MJ Saaranen, V Pérez, J Ojeda, FJ Bustos, ...
The EMBO journal 35 (8), 845-865, 2016
1182016
Early pathogenesis in the adult‐onset neurodegenerative disease amyotrophic lateral sclerosis
B Van Zundert, P Izaurieta, E Fritz, FJ Alvarez
Journal of cellular biochemistry 113 (11), 3301-3312, 2012
972012
Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling
F Rojas, D Gonzalez, N Cortes, E Ampuero, DE Hernández, E Fritz, ...
Frontiers in cellular neuroscience 9, 203, 2015
952015
Epigenetic control of the bone-master Runx2 gene during osteoblast-lineage commitment by the histone demethylase JARID1B/KDM5B
A Rojas, R Aguilar, B Henriquez, JB Lian, JL Stein, GS Stein, ...
Journal of biological chemistry 290 (47), 28329-28342, 2015
942015
Dissecting the role of redox signaling in neuronal development
DA Bórquez, PJ Urrutia, C Wilson, B Van Zundert, MT Núñez, ...
Journal of neurochemistry 137 (4), 506-517, 2016
882016
Differential roles of NMDA receptor subtypes NR2A and NR2B in dendritic branch development and requirement of RasGRF1
FJ Sepulveda, FJ Bustos, E Inostroza, FA Zúñiga, RL Neve, M Montecino, ...
Journal of neurophysiology 103 (4), 1758-1770, 2010
872010
Alterations in the motor neuron–renshaw cell circuit in the Sod1G93A mouse model
H Wootz, E FitzSimons‐Kantamneni, M Larhammar, TM Rotterman, ...
Journal of Comparative Neurology 521 (7), 1449-1469, 2013
842013
Changes on the properties of glycine receptors during neuronal development
LG Aguayo, B Van Zundert, JC Tapia, MA Carrasco, FJ Alvarez
Brain research reviews 47 (1-3), 33-45, 2004
832004
Silencing strategies for therapy of SOD1-mediated ALS
B van Zundert, RH Brown Jr
Neuroscience Letters 636, 32-39, 2017
822017
Pathogenicity of Lupus Anti–Ribosomal P Antibodies: Role of Cross‐Reacting Neuronal Surface P Antigen in Glutamatergic Transmission and Plasticity in a Mouse Model
F Segovia‐Miranda, F Serrano, A Dyrda, E Ampuero, C Retamal, ...
Arthritis & rheumatology 67 (6), 1598-1610, 2015
812015
PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors
FJ Bustos, L Varela-Nallar, M Campos, B Henriquez, M Phillips, C Opazo, ...
PLoS One 9 (4), e94037, 2014
812014
Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain of humans and mice exposed to particulate urban air pollution
L Calderón-Garcidueñas, A Herrera-Soto, N Jury, BA Maher, ...
Environmental research 183, 109226, 2020
772020
αVβ3 Integrin regulates astrocyte reactivity
R Lagos-Cabré, A Alvarez, M Kong, F Burgos-Bravo, A Cárdenas, ...
Journal of neuroinflammation 14, 1-13, 2017
742017
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