Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages EL Mills, B Kelly, A Logan, ASH Costa, M Varma, CE Bryant, ... Cell 167 (2), 457-470. e13, 2016 | 1667 | 2016 |
Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project MB Gerstein, ZJ Lu, EL Van Nostrand, C Cheng, BI Arshinoff, T Liu, ... Science 330 (6012), 1775-1787, 2010 | 1095 | 2010 |
Differential chromatin marking of introns and expressed exons by H3K36me3 P Kolasinska-Zwierz, T Down, I Latorre, T Liu, XS Liu, J Ahringer Nature genetics 41 (3), 376-381, 2009 | 800 | 2009 |
An assessment of histone-modification antibody quality TA Egelhofer, A Minoda, S Klugman, K Lee, P Kolasinska-Zwierz, ... Nature structural & molecular biology 18 (1), 91-93, 2011 | 480 | 2011 |
Comparative analysis of metazoan chromatin organization JWK Ho, YL Jung, T Liu, BH Alver, S Lee, K Ikegami, KA Sohn, A Minoda, ... Nature 512 (7515), 449-452, 2014 | 415 | 2014 |
Broad chromosomal domains of histone modification patterns in C. elegans T Liu, A Rechtsteiner, TA Egelhofer, A Vielle, I Latorre, MS Cheung, ... Genome research 21 (2), 227-236, 2011 | 301 | 2011 |
Systematic bias in high-throughput sequencing data and its correction by BEADS MS Cheung, TA Down, I Latorre, J Ahringer Nucleic acids research 39 (15), e103-e103, 2011 | 177 | 2011 |
Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells IJ Latorre, MH Roh, KK Frese, RS Weiss, B Margolis, RT Javier Journal of cell science 118 (18), 4283-4293, 2005 | 170 | 2005 |
Spatial and temporal mapping of human innate lymphoid cells reveals elements of tissue specificity NA Yudanin, F Schmitz, AL Flamar, JJC Thome, ET Wojno, JB Moeller, ... Immunity 50 (2), 505-519. e4, 2019 | 166 | 2019 |
Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein KK Frese, SS Lee, DL Thomas, IJ Latorre, RS Weiss, BA Glaunsinger, ... Oncogene 22 (5), 710-721, 2003 | 130 | 2003 |
Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs‐large tumor suppressor KK Frese, IJ Latorre, SH Chung, G Caruana, A Bernstein, SN Jones, ... The EMBO journal 25 (6), 1406-1417, 2006 | 91 | 2006 |
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics SY Kuo, AB Castoreno, LN Aldrich, KG Lassen, G Goel, V Dančík, ... Proceedings of the National Academy of Sciences 112 (31), E4281-E4287, 2015 | 69 | 2015 |
Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo TB Sundberg, Y Liang, H Wu, HG Choi, ND Kim, T Sim, L Johannessen, ... ACS chemical biology 11 (8), 2105-2111, 2016 | 66 | 2016 |
The DREAM complex promotes gene body H2A. Z for target repression I Latorre, MA Chesney, JM Garrigues, P Stempor, A Appert, ... Genes & development 29 (5), 495-500, 2015 | 66 | 2015 |
Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells L Johannessen, TB Sundberg, DJ O'Connell, R Kolde, J Berstler, ... Nature chemical biology 13 (10), 1102-1108, 2017 | 57 | 2017 |
Discovery of a small-molecule probe for V-ATPase function LN Aldrich, SY Kuo, AB Castoreno, G Goel, P Kuballa, MG Rees, ... Journal of the American chemical society 137 (16), 5563-5568, 2015 | 48 | 2015 |
A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line Y Song, K Subramanian, MJ Berberich, S Rodriguez, IJ Latorre, CM Luria, ... Scientific Data 6 (1), 1-17, 2019 | 41 | 2019 |
Single-cell transcriptomic profiles reveal changes associated with BCG-induced trained immunity and protective effects in circulating monocytes L Kong, SJ Moorlag, A Lefkovith, B Li, V Matzaraki, L van Emst, HA Kang, ... Cell reports 37 (7), 2021 | 36 | 2021 |
Repurposing mitochondria from ATP production to ROS generation drives a pro-inflammatory phenotype in macrophages that depends on succinate oxidation by complex II EL Mills, B Kelly, A Logan, ASH Costa, M Varma, CE Bryant, ... Cell 167 (2), 457, 2016 | 32 | 2016 |
Simultaneous pathway activity inference and gene expression analysis using RNA sequencing DJ O’Connell, R Kolde, M Sooknah, DB Graham, TB Sundberg, IJ Latorre, ... Cell systems 2 (5), 323-334, 2016 | 27 | 2016 |