Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920) GHM Salvador, AAS Gomes, W Bryan-Quirós, J Fernández, MR Lewin, ... Scientific Reports 9 (1), 17203, 2019 | 61 | 2019 |
Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca2+-binding loop region for the catalytically inactive Lys49-PLA2s CAH Fernandes, DP Marchi-Salvador, GM Salvador, MCO Silva, ... Journal of Structural Biology 171 (1), 31-43, 2010 | 58 | 2010 |
Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism GHM Salvador, TR Dreyer, AAS Gomes, WLG Cavalcante, JI Dos Santos, ... Scientific reports 8 (1), 10317, 2018 | 32 | 2018 |
Structural and functional evidence for membrane docking and disruption sites on phospholipase A2-like proteins revealed by complexation with the inhibitor suramin GHM Salvador, TR Dreyer, WLG Cavalcante, FF Matioli, JI Dos Santos, ... Acta Crystallographica Section D: Biological Crystallography 71 (10), 2066-2078, 2015 | 32 | 2015 |
Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A2-like proteins using functional, structural and bioinformatics approaches GHM Salvador, FF Cardoso, AA Gomes, WLG Cavalcante, M Gallacci, ... Scientific Reports 9 (1), 510, 2019 | 31 | 2019 |
The synthetic varespladib molecule is a multi-functional inhibitor for PLA2 and PLA2-like ophidic toxins GHM Salvador, RJ Borges, B Lomonte, MR Lewin, MRM Fontes Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (7), 129913, 2021 | 27 | 2021 |
Structural and functional studies with mytoxin II from Bothrops moojeni reveal remarkable similarities and differences compared to other catalytically inactive phospholipases … GHM Salvador, WLG Cavalcante, JI Dos Santos, M Gallacci, AM Soares, ... Toxicon 72, 52-63, 2013 | 27 | 2013 |
Structural basis of phospholipase A2-like myotoxin inhibition by chicoric acid, a novel potent inhibitor of ophidian toxins FF Cardoso, RJ Borges, TR Dreyer, GHM Salvador, WLG Cavalcante, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (12), 2728-2737, 2018 | 23 | 2018 |
Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative “myotoxic cluster” GHM Salvador, JI Dos Santos, B Lomonte, MRM Fontes Biochimie 133, 95-102, 2017 | 23 | 2017 |
Secondary hemostasis studies of crude venom and isolated proteins from the snake Crotalus durissus terrificus IDL Sousa, AR Barbosa, GHM Salvador, BEF Frihling, PH Santa-Rita, ... International journal of biological macromolecules 131, 127-133, 2019 | 20 | 2019 |
Structural and Phylogenetic Studies with MjTX-I Reveal a Multi-Oligomeric Toxin – a Novel Feature in Lys49-PLA2s Protein Class GHM Salvador, CAH Fernandes, AJ Magro, DP Marchi-Salvador, ... PLoS One 8 (4), e60610, 2013 | 20 | 2013 |
Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin GHM Salvador, JI Dos Santos, RJ Borges, MRM Fontes Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1866 (3), 473-481, 2018 | 15 | 2018 |
Crystallization and preliminary X-ray diffraction analysis of crotoxin B from Crotalus durissus collilineatus venom GHM Salvador, CAH Fernandes, LC Corrêa, NA Santos-Filho, AM Soares, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009 | 10 | 2009 |
Biochemical, pharmacological and structural characterization of BmooMP-I, a new P–I metalloproteinase from bothrops moojeni venom GHM Salvador, RJ Borges, MMC Eulálio, LD Dos Santos, MRM Fontes Biochimie 179, 54-64, 2020 | 9 | 2020 |
Structural basis of the myotoxic inhibition of the Bothrops pirajai PrTX-I by the synthetic varespladib GHM Salvador, ÊKR Pinto, PL Ortolani, CL Fortes-Dias, WLG Cavalcante, ... Biochimie 207, 1-10, 2023 | 7 | 2023 |
BthTX-II from bothrops jararacussu venom has variants with different oligomeric assemblies: an example of snake venom phospholipases A2 versatility RJ Borges, GHM Salvador, HB Campanelli, DC Pimenta, ... International Journal of Biological Macromolecules 191, 255-266, 2021 | 7 | 2021 |
Preliminary X-ray crystallographic studies of a tetrameric phospholipase A2 formed by two isoforms of crotoxin B from Crotalus durissus terrificus venom DP Marchi-Salvador, LC Corrêa, GHM Salvador, AJ Magro, CZ Oliveira, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2007 | 7 | 2007 |
Crystallization and preliminary X-ray diffraction studies of BmooPLA2-I, a platelet-aggregation inhibitor and hypotensive phospholipase A2 from Bothrops moojeni venom GHM Salvador, DP Marchi-Salvador, LB Silveira, AM Soares, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 5 | 2011 |
SEQUENCE SLIDER: integration of structural and genetic data to characterize isoforms from natural sources RJ Borges, GHM Salvador, DC Pimenta, LD Dos Santos, MRM Fontes, ... Nucleic acids research 50 (9), e50-e50, 2022 | 3 | 2022 |
Malignant hyperthermia in bariatric surgery: a case study with clinical, pathophysiological, biochemical and biophysical correlations PEA Oliveira, GHM Salvador, DP Marchi-Salvador Journal of Medical Cases 11 (12), 379, 2020 | 3 | 2020 |