Mario Niepel

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Peter K. SorgerHarvard Medical SchoolDirección de correo verificada de hms.harvard.edu
Marc HafnerGenentechDirección de correo verificada de gene.com
Avi Ma'ayanProfessor, Icahn School of Medicine at Mount Sinai, New York, NYDirección de correo verificada de mssm.edu
Qiaonan DuanNuMedii, Inc.Dirección de correo verificada de icahn.mssm.edu
Alvin LuTango Therapeutics LLC, Harvard UniversityDirección de correo verificada de alumni.harvard.edu
Tim WigleRibon TherapeuticsDirección de correo verificada de ribontx.com
Jeremy L MuhlichDirector of Software Engineering, Harvard Medical School Laboratory of Systems PharmacologyDirección de correo verificada de hms.harvard.edu
Laurie SchenkelMedicinal Chemistry, AmgenDirección de correo verificada de amgen.com
Evan PaullPlatform Leader AI / ML, CZI Biohub NYDirección de correo verificada de czbiohub.org
qingsong LiuHigh Magnetic Field Laboratory, CASDirección de correo verificada de hmfl.ac.cn
Nicolas F. FernandezBroad Institute of MIT and HarvardDirección de correo verificada de broadinstitute.org
Purushottam DixitYale UniversityDirección de correo verificada de yale.edu
Todd GolubBroad InstituteDirección de correo verificada de broadinstitute.org
Zichen WangAmazonDirección de correo verificada de mssm.edu
Joshua M StuartUC Santa Cruz Genomics InstituteDirección de correo verificada de ucsc.edu
Bin GuiRibon TherapeuticsDirección de correo verificada de ribontx.com
Brian ChaitCamille and Henry Dreyfus Professor, The Rockefeller UniversityDirección de correo verificada de rockefeller.edu
Ulrik B NielsenMerrimack PharmaceuticalsDirección de correo verificada de merrimackpharma.com
Douglas LauffenburgerMITDirección de correo verificada de mit.edu
Mohammad Fallahi-SichaniAssociate Professor of Biomedical Engineering, University of VirginiaDirección de correo verificada de virginia.edu

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Mario Niepel

Ribon Therapeutics

Dirección de correo verificada de ribontx.com - Página principal

drug discovery drug development cancer research kinase inhibitors signal transduction


Título Ordenar por citas Ordenar por año Ordenar por título	Citado por Citado por	Año
The nuclear pore complex: bridging nuclear transport and gene regulation C Strambio-De-Castillia, M Niepel, MP Rout Nature reviews Molecular cell biology 11 (7), 490-501, 2010	682	2010
Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs M Hafner, M Niepel, M Chung, PK Sorger Nature methods 13 (6), 521-527, 2016	629	2016
Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data WW Chen, B Schoeberl, PJ Jasper, M Niepel, UB Nielsen, ... Molecular systems biology 5 (1), 239, 2009	477	2009
The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ... Cell systems 6 (1), 13-24, 2018	414	2018
Classic and contemporary approaches to modeling biochemical reactions WW Chen, M Niepel, PK Sorger Genes & development 24 (17), 1861-1875, 2010	387	2010
Discovery of potent and selective covalent inhibitors of JNK T Zhang, F Inesta-Vaquera, M Niepel, J Zhang, SB Ficarro, T Machleidt, ... Chemistry & biology 19 (1), 140-154, 2012	376	2012
LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures Q Duan, C Flynn, M Niepel, M Hafner, JL Muhlich, NF Fernandez, ... Nucleic acids research 42 (W1), W449-W460, 2014	337	2014
L1000CDS2: LINCS L1000 characteristic direction signatures search engine Q Duan, SP Reid, NR Clark, Z Wang, NF Fernandez, AD Rouillard, ... NPJ systems biology and applications 2 (1), 1-12, 2016	293	2016
Non-genetic cell-to-cell variability and the consequences for pharmacology M Niepel, SL Spencer, PK Sorger Current opinion in chemical biology 13 (5-6), 556-561, 2009	262	2009
Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR Q Liu, C Xu, S Kirubakaran, X Zhang, W Hur, Y Liu, NP Kwiatkowski, ... Cancer research 73 (8), 2574-2586, 2013	239	2013
ADP‐ribosyltransferases, an update on function and nomenclature B Lüscher, I Ahel, M Altmeyer, A Ashworth, P Bai, P Chang, M Cohen, ... The FEBS journal 289 (23), 7399-7410, 2022	226	2022
Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE) EO Paull, DE Carlin, M Niepel, PK Sorger, D Haussler, JM Stuart Bioinformatics 29 (21), 2757-2764, 2013	210	2013
Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway T Shi, M Niepel, JE McDermott, Y Gao, CD Nicora, WB Chrisler, ... Science Signaling 9 (436), rs6-rs6, 2016	146	2016
Identification and characterization of the functional elements within the tobacco etch virus 5′ leader required for cap-independent translation M Niepel, DR Gallie Journal of virology 73 (11), 9080-9088, 1999	135	1999
A multi-center study on the reproducibility of drug-response assays in mammalian cell lines M Niepel, M Hafner, CE Mills, K Subramanian, EH Williams, M Chung, ... Cell systems 9 (1), 35-48. e5, 2019	133	2019
Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics Q Liu, S Kirubakaran, W Hur, M Niepel, K Westover, CC Thoreen, J Wang, ... Journal of Biological Chemistry 287 (13), 9742-9752, 2012	129	2012
The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome M Niepel, KR Molloy, R Williams, JC Farr, AC Meinema, N Vecchietti, ... Molecular Biology of the Cell, mbc. E13-07-0412, 2013	123	2013
A cell cycle phosphoproteome of the yeast centrosome JM Keck, MH Jones, CCL Wong, J Binkley, D Chen, SL Jaspersen, ... Science 332 (6037), 1557, 2011	123	2011
Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines M Niepel, M Hafner, EA Pace, M Chung, DH Chai, L Zhou, B Schoeberl, ... Science signaling 6 (294), ra84-ra84, 2013	110	2013
Systematic analysis of BRAF^V^600E melanomas reveals a role for JNK/c‐Jun pathway in adaptive resistance to drug‐induced apoptosis M Fallahi‐Sichani, NJ Moerke, M Niepel, T Zhang, NS Gray, PK Sorger Molecular systems biology 11 (3), 797, 2015	108	2015

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