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Alexander W Bird
Alexander W Bird
Silence Therapeutics
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Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair
AW Bird, DY Yu, MG Pray-Grant, Q Qiu, KE Harmon, PC Megee, PA Grant, ...
Nature 419 (6905), 411-415, 2002
6812002
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals
I Poser, M Sarov, JRA Hutchins, JK Hériché, Y Toyoda, A Pozniakovsky, ...
Nature methods 5 (5), 409-415, 2008
6602008
Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions
NC Hubner, AW Bird, J Cox, B Splettstoesser, P Bandilla, I Poser, ...
Journal of Cell Biology 189 (4), 739-754, 2010
4902010
Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A
AW Bird, AA Hyman
The Journal of cell biology 182 (2), 289-300, 2008
2712008
Cryo-EM reveals how human cytoplasmic dynein is auto-inhibited and activated
K Zhang, HE Foster, A Rondelet, SE Lacey, N Bahi-Buisson, AW Bird, ...
Cell 169 (7), 1303-1314. e18, 2017
2472017
The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis
F Zhu, S Lawo, A Bird, D Pinchev, A Ralph, C Richter, T Müller-Reichert, ...
Current Biology 18 (2), 136-141, 2008
1992008
Natural product–inspired cascade synthesis yields modulators of centrosome integrity
H Dückert, V Pries, V Khedkar, S Menninger, H Bruss, AW Bird, Z Maliga, ...
Nature chemical biology 8 (2), 179-184, 2012
1342012
Tpx2 controls spindle integrity, genome stability, and tumor development
C Aguirre-Portolés, AW Bird, A Hyman, M Cañamero, I Pérez de Castro, ...
Cancer research 72 (6), 1518-1528, 2012
1172012
High-efficiency counterselection recombineering for site-directed mutagenesis in bacterial artificial chromosomes
AW Bird, A Erler, J Fu, JK Hériché, M Maresca, Y Zhang, AA Hyman, ...
Nature methods 9 (1), 103-109, 2012
712012
CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading.
D Pan, K Klare, A Petrovic, A Take, K Walstein, P Singh, A Rondelet, ...
eLife 6, e23352, 2017
682017
GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration
M Scolz, PO Widlund, S Piazza, DR Bublik, S Reber, LY Peche, Y Ciani, ...
PLoS one 7 (12), e51259, 2012
652012
Polycomb group ring finger 1 cooperates with Runx1 in regulating differentiation and self-renewal of hematopoietic cells
K Ross, AK Sedello, GP Todd, M Paszkowski-Rogacz, AW Bird, L Ding, ...
Blood, The Journal of the American Society of Hematology 119 (18), 4152-4161, 2012
612012
GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK
S Bendre, A Rondelet, C Hall, N Schmidt, YC Lin, GJ Brouhard, AW Bird
Journal of Cell Biology 215 (5), 631-647, 2016
452016
The aurora-A/TPX2 Axis directs spindle orientation in adherent human cells by regulating NuMA and microtubule stability
F Polverino, FD Naso, IA Asteriti, V Palmerini, D Singh, D Valente, ...
Current Biology 31 (3), 658-667. e5, 2021
252021
Clathrin’s adaptor interaction sites are repurposed to stabilize microtubules during mitosis
A Rondelet, YC Lin, D Singh, AT Porfetye, HC Thakur, A Hecker, ...
Journal of Cell Biology 219 (2), 2020
162020
Discriminative semi-markov models for automated mitotic phase labelling
A El-Labban, A Zisserman, Y Toyoda, AW Bird, A Hyman
2012 9th IEEE International Symposium on Biomedical Imaging (ISBI), 760-763, 2012
162012
Destabilization of long astral microtubules via Cdk1-dependent removal of GTSE1 from their plus ends facilitates prometaphase spindle orientation
D Singh, N Schmidt, F Müller, T Bange, AW Bird
Current Biology 31 (4), 766-781. e8, 2021
142021
Dynamic time warping for automated cell cycle labelling
A El-Labban, A Zisserman, Y Toyoda, AW Bird, A Hyman
Microscopic Image Analysis with Applications in Biology, 580-583, 2011
82011
Temporal models for mitotic phase labelling
A El-Labban, A Zisserman, Y Toyoda, AW Bird, A Hyman
Medical image analysis 18 (7), 977-988, 2014
52014
ESI mutagenesis: A one-step method for introducing point mutations into bacterial artificial chromosome transgenes
A Rondelet, A Pozniakovsky, M Leuschner, I Poser, A Ssykor, J Berlitz, ...
bioRxiv, 844282, 2019
32019
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Artículos 1–20