p115 RhoGEF, a GTPase activating protein for Gα12 and Gα13 T Kozasa, X Jiang, MJ Hart, PM Sternweis, WD Singer, AG Gilman, ... Science 280 (5372), 2109-2111, 1998 | 1078 | 1998 |
Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Gα13 MJ Hart, X Jiang, T Kozasa, W Roscoe, WD Singer, AG Gilman, ... Science 280 (5372), 2112-2114, 1998 | 1038 | 1998 |
Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D WD Singer, HA Brown, and, PC Sternweis Annual Review of Biochemistry 66 (1), 475-509, 1997 | 493 | 1997 |
Regulation of Phospholipase D by Protein Kinase C Is Synergistic with ADP-ribosylation Factor and Independent of Protein Kinase Activity (∗) WD Singer, HA Brown, X Jiang, PC Sternweis Journal of Biological Chemistry 271 (8), 4504-4510, 1996 | 298 | 1996 |
Resolved Phospholipase D Activity Is Modulated by Cytosolic Factors Other than Arf (∗) WD Singer, HA Brown, GM Bokoch, PC Sternweis Journal of Biological Chemistry 270 (25), 14944-14950, 1995 | 166 | 1995 |
Structure of the p115RhoGEF rgRGS domain–Gα13/i1 chimera complex suggests convergent evolution of a GTPase activator Z Chen, WD Singer, PC Sternweis, SR Sprang Nature Structural & Molecular Biology 12 (2), 191-197, 2005 | 131 | 2005 |
Purification and characterization of the alpha subunit of G13. WD Singer, RT Miller, PC Sternweis Journal of Biological Chemistry 269 (31), 19796-19802, 1994 | 95 | 1994 |
Structural and biochemical analyses reveal the mechanism of glutathione S-transferase Pi 1 inhibition by the anti-cancer compound piperlongumine W Harshbarger, S Gondi, SB Ficarro, J Hunter, D Udayakumar, D Gurbani, ... Journal of Biological Chemistry 292 (1), 112-120, 2017 | 84 | 2017 |
Regulation of Rho guanine nucleotide exchange factors by G proteins PC Sternweis, AM Carter, Z Chen, SM Danesh, YF Hsiung, WD Singer Advances in protein chemistry 74, 189-228, 2007 | 69 | 2007 |
Binding of vinblastine to stabilized microtubules. WD Singer, MA Jordan, L Wilson, RH Himes Molecular pharmacology 36 (3), 366-370, 1989 | 64 | 1989 |
The monomeric G-proteins Rac1 and/or Cdc42 are required for the inhibition of voltage-dependent calcium current by bradykinin MA Wilk-Blaszczak, WD Singer, T Quill, B Miller, JA Frost, PC Sternweis, ... The Journal of Neuroscience 17 (11), 4094-4100, 1997 | 62 | 1997 |
Cellular uptake and tubulin binding properties of four Vinca alkaloids WD Singer, RH Himes Biochemical pharmacology 43 (3), 545-551, 1992 | 62 | 1992 |
Recognition of the activated states of Gα13 by the rgRGS domain of PDZRhoGEF Z Chen, WD Singer, SM Danesh, PC Sternweis, SR Sprang Structure 16 (10), 1532-1543, 2008 | 58 | 2008 |
The G protein G13 mediates inhibition of voltage-dependent calcium current by bradykinin MA Wilk-Blaszczak, WD Singer, S Gutowski, PC Sternweis, F Belardetti Neuron 13 (5), 1215-1224, 1994 | 56 | 1994 |
Mapping the Gα13 binding interface of the rgRGS domain of p115RhoGEF Z Chen, WD Singer, CD Wells, SR Sprang, PC Sternweis Journal of Biological Chemistry 278 (11), 9912-9919, 2003 | 51 | 2003 |
G alpha q and G alpha 13 regulate NHE-1 and intracellular calcium in epithelial cells K Kitamura, WD Singer, A Cano, RT Miller Am J. Physiol. 268, C101 - C110, 1995 | 51 | 1995 |
Endothelin-B receptors activate Gα13 K Kitamura, N Shiraishi, WD Singer, ME Handlogten, K Tomita, RT Miller American Journal of Physiology-Cell Physiology 276 (4), C930-C937, 1999 | 41 | 1999 |
Effect of solution variables on the binding of vinblastine to tubulin WD Singer, RT Hersh, RH Himes Biochemical pharmacology 37 (13), 2691-2696, 1988 | 39 | 1988 |
Gq/11 and PLC-beta 1 mediate the substance P-induced inhibition of an inward rectifier K+ channel in brain neurons K Takano, J Yasufuku-Takano, T Kozasa, WD Singer, S Nakajima, ... Journal of neurophysiology 76 (3), 2131-2136, 1996 | 37 | 1996 |
Induction of Inducible Nitric-oxide Synthase by the Heterotrimeric G Protein Gα13*(∗) K Kitamura, WD Singer, RA Star, S Muallem, RT Miller Journal of Biological Chemistry 271 (13), 7412-7415, 1996 | 33 | 1996 |