Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives JE Choby, J Howard‐Anderson, DS Weiss Journal of internal medicine 287 (3), 283-300, 2020 | 387 | 2020 |
Heme synthesis and acquisition in bacterial pathogens JE Choby, EP Skaar Journal of molecular biology 428 (17), 3408-3428, 2016 | 282 | 2016 |
Widespread cefiderocol heteroresistance in carbapenem-resistant Gram-negative pathogens JE Choby, T Ozturk, SW Satola, JT Jacob, DS Weiss The Lancet Infectious Diseases 21 (5), 597-598, 2021 | 67 | 2021 |
Two-Component System Cross-Regulation Integrates Bacillus anthracis Response to Heme and Cell Envelope Stress LA Mike, JE Choby, PR Brinkman, LQ Olive, BF Dutter, SJ Ivan, CM Gibbs, ... PLoS pathogens 10 (3), e1004044, 2014 | 52 | 2014 |
Manganese Detoxification by MntE Is Critical for Resistance to Oxidative Stress and Virulence of Staphylococcus aureus CM Grunenwald, JE Choby, LJ Juttukonda, WN Beavers, A Weiss, ... MBio 10 (1), 10.1128/mbio. 02915-18, 2019 | 49 | 2019 |
Targeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia RJ Watters, TE Fox, SF Tan, S Shanmugavelandy, JE Choby, K Broeg, ... Leukemia & lymphoma 54 (6), 1288-1296, 2013 | 41 | 2013 |
A small-molecule inhibitor of iron-sulfur cluster assembly uncovers a link between virulence regulation and metabolism in Staphylococcus aureus JE Choby, LA Mike, AA Mashruwala, BF Dutter, PM Dunman, ... Cell chemical biology 23 (11), 1351-1361, 2016 | 35 | 2016 |
Does cefiderocol heteroresistance explain the discrepancy between the APEKS-NP and CREDIBLE-CR clinical trial results? JE Choby, T Ozturk, SW Satola, JT Jacob, DS Weiss The Lancet Microbe 2 (12), e648-e649, 2021 | 25 | 2021 |
Staphylococcus aureus HemX Modulates Glutamyl-tRNA Reductase Abundance To Regulate Heme Biosynthesis JE Choby, CM Grunenwald, AI Celis, SY Gerdes, JL DuBois, EP Skaar MBio 9 (1), 10.1128/mbio. 02287-17, 2018 | 23 | 2018 |
Control of Metabolite Flux during the Final Steps of Heme b Biosynthesis in Gram-Positive Bacteria AI Celis, JE Choby, J Kentro, EP Skaar, JL DuBois Biochemistry 58 (52), 5259-5270, 2019 | 17 | 2019 |
Molecular basis for the evolution of species-specific hemoglobin capture by Staphylococcus aureus JE Choby, HB Buechi, AJ Farrand, EP Skaar, MF Barber MBio 9 (6), 10.1128/mbio. 01524-18, 2018 | 17 | 2018 |
Staphylococcus Aureus Coproporphyrinogen III oxidase is required for aerobic and anaerobic heme synthesis JE Choby, EP Skaar Msphere 4 (4), 10.1128/msphere. 00235-19, 2019 | 11 | 2019 |
A Phenome-Wide Association Study Uncovers a Pathological Role of Coagulation Factor X during Acinetobacter baumannii Infection JE Choby, AJ Monteith, LE Himmel, P Margaritis, JK Shirey-Rice, ... Infection and Immunity 87 (5), 10.1128/iai. 00031-19, 2019 | 9 | 2019 |
Translocation of gut commensal bacteria to the brain M Thapa, A Kumari, CY Chin, JE Choby, F Jin, B Bogati, DM Chopyk, ... bioRxiv, 2023 | 6 | 2023 |
Heteroresistance via beta-lactamase gene amplification threatens the beta-lactam pipeline JE Choby, T Ozturk, CN Abbott, SW Satola, DS Weiss bioRxiv, 2022, 2022 | 4 | 2022 |
Antibiotic-selected gene amplification heightens metal resistance DA Hufnagel, JE Choby, S Hao, AF Johnson, EM Burd, C Langelier, ... Mbio 12 (1), 10.1128/mbio. 02994-20, 2021 | 3 | 2021 |
Theoretical considerations and empirical predictions of the pharmaco-and population dynamics of heteroresistance BR Levin, BA Berryhill, T Gil-Gil, JA Manuel, AP Smith, JE Choby, ... Proceedings of the National Academy of Sciences 121 (16), e2318600121, 2024 | 2 | 2024 |
Maintenance of heme homeostasis in Staphylococcus aureus through post-translational regulation of glutamyl-tRNA reductase CS Leasure, CM Grunenwald, JE Choby, JD Sauer, EP Skaar Journal of Bacteriology 205 (9), e00171-23, 2023 | 1 | 2023 |
Molecular basis for the evolution of species-specific hemoglobin capture by pathogenic Staphylococcus JE Choby, HB Buechi, AJ Farrand, EP Skaar, MF Barber Biorxiv, 339705, 2018 | 1 | 2018 |
Antibiotic Heteroresistance: What Is It and How Does It Impact Patients? J Choby MJH Life Sciences, 2024 | | 2024 |