| Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei D Zink, MD Amaral, A Englmann, S Lang, LA Clarke, C Rudolph, F Alt, ... The Journal of cell biology 166 (6), 815-825, 2004 | 324 | 2004 |
| PCR amplification introduces errors into mononucleotide and dinucleotide repeat sequences LA Clarke, CS Rebelo, J Goncalves, MG Boavida, P Jordan Molecular Pathology 54 (5), 351, 2001 | 179 | 2001 |
| Magnetic field-assisted DNA hybridisation and simultaneous detection using micron-sized spin-valve sensors and magnetic nanoparticles DL Graham, HA Ferreira, N Feliciano, PP Freitas, LA Clarke, MD Amaral Sensors and Actuators B: Chemical 107 (2), 936-944, 2005 | 130 | 2005 |
| Measurements of functional responses in Human primary lung cells as a basis for personalized therapy for cystic fibrosis NT Awatade, I Uliyakina, CM Farinha, LA Clarke, K Mendes, A Solé, ... EBioMedicine 2 (2), 147-153, 2015 | 91 | 2015 |
| Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies LA Clarke, L Sousa, C Barreto, MD Amaral Respiratory research 14, 1-19, 2013 | 91 | 2013 |
| Correction of a cystic fibrosis splicing mutation by antisense oligonucleotides S Igreja, LA Clarke, HM Botelho, L Marques, MD Amaral Human mutation 37 (2), 209-215, 2016 | 87 | 2016 |
| BO-LSTM: classifying relations via long short-term memory networks along biomedical ontologies A Lamurias, D Sousa, LA Clarke, FM Couto BMC bioinformatics 20, 1-12, 2019 | 75 | 2019 |
| Magnetoresistive DNA chips PP Freitas, HA Ferreira, DL Graham, LA Clarke, MD Amaral, V Martins, ... Magnetoelectronics, 331-386, 2004 | 74* | 2004 |
| Detection of cystic fibrosis related DNA targets using AC field focusing of magnetic labels and spin-valve sensors HA Ferreira, DL Graham, N Feliciano, LA Clarke, MD Amaral, PP Freitas IEEE Transactions on Magnetics 41 (10), 4140-4142, 2005 | 69* | 2005 |
| High-content siRNA screen reveals global ENaC regulators and potential cystic fibrosis therapy targets J Almaça, D Faria, M Sousa, I Uliyakina, C Conrad, L Sirianant, LA Clarke, ... Cell 154 (6), 1390-1400, 2013 | 64 | 2013 |
| Human epididymis protein 4: a novel serum inflammatory biomarker in cystic fibrosis B Nagy Jr, B Nagy, L Fila, LA Clarke, F Gönczy, O Bede, D Nagy, ... Chest 150 (3), 661-672, 2016 | 61 | 2016 |
| Rapid DNA hybridization based on ac field focusing of magnetically labeled target DNA HA Ferreira, N Feliciano, DL Graham, LA Clarke, MD Amaral, PP Freitas Applied Physics Letters 87 (1), 2005 | 58 | 2005 |
| Methods for RNA extraction, cDNA preparation and analysis of CFTR transcripts AS Ramalho, S Beck, CM Farinha, LA Clarke, GD Heda, B Steiner, J Sanz, ... Journal of Cystic Fibrosis 3, 11-15, 2004 | 58 | 2004 |
| Extracting microRNA-gene relations from biomedical literature using distant supervision A Lamurias, LA Clarke, FM Couto PloS one 12 (3), e0171929, 2017 | 54 | 2017 |
| F508del-CFTR increases intracellular Ca2+ signaling that causes enhanced calcium-dependent Cl− conductance in cystic fibrosis JR Martins, P Kongsuphol, E Sammels, S Dahimène, F AlDehni, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (11 …, 2011 | 51 | 2011 |
| Transcriptome meta-analysis reveals common differential and global gene expression profiles in cystic fibrosis and other respiratory disorders and identifies CFTR regulators LA Clarke, HM Botelho, L Sousa, AO Falcao, MD Amaral Genomics 106 (5), 268-277, 2015 | 50 | 2015 |
| Magnetic biosensors for genetic screening of cystic fibrosis L Lagae, R Wirix-Speetjens, CX Liu, W Laureyn, G Borghs, S Harvey, ... IEE Proceedings-Circuits, Devices and Systems 152 (4), 393-400, 2005 | 50 | 2005 |
| Mutant CFTR Drives TWIST1 mediated epithelial–mesenchymal transition MC Quaresma, I Pankonien, LA Clarke, LS Sousa, IAL Silva, V Railean, ... Cell Death & Disease 11 (10), 920, 2020 | 47 | 2020 |
| TMEM16A chloride channel does not drive mucus production FB Simões, MC Quaresma, LA Clarke, IAL Silva, I Pankonien, V Railean, ... Life science alliance 2 (6), 2019 | 39 | 2019 |
| The function of bill-wiping I Cuthill, M Witter, L Clarke Animal Behaviour 43 (1), 103-115, 1992 | 38 | 1992 |
Margarida AmaralProfessor of Molecular Biology, Faculty of Sciences, University of LisboaVerified email at fc.ul.pt
