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Counter-regulatory renin–angiotensin system in cardiovascular disease
M Paz Ocaranza, JA Riquelme, L García, JE Jalil, M Chiong, RAS Santos, ...
Nature Reviews Cardiology 17 (2), 116-129, 2020
5102020
Enalapril attenuates downregulation of angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat
MP Ocaranza, I Godoy, JE Jalil, M Varas, P Collantes, M Pinto, M Roman, ...
Hypertension 48 (4), 572-578, 2006
3222006
ACE2 and vasoactive peptides: novel players in cardiovascular/renal remodeling and hypertension
E Mendoza-Torres, A Oyarzún, D Mondaca-Ruff, A Azocar, PF Castro, ...
Therapeutic advances in cardiovascular disease 9 (4), 217-237, 2015
1772015
Cardiac hypertrophy: molecular and cellular events
JE Carreño, F Apablaza, MP Ocaranza, JE Jalil
Revista Española de Cardiología (English Edition) 59 (5), 473-486, 2006
1472006
Angiotensin-(1–9) regulates cardiac hypertrophy in vivo and in vitro
MP Ocaranza, S Lavandero, JE Jalil, J Moya, M Pinto, U Novoa, ...
Journal of hypertension 28 (5), 1054-1064, 2010
1282010
Angiotensin-(1–9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis
MP Ocaranza, J Moya, V Barrientos, R Alzamora, D Hevia, C Morales, ...
Journal of hypertension 32 (4), 771-783, 2014
1182014
Increased levels of oxidative stress, subclinical inflammation, and myocardial fibrosis markers in primary aldosteronism patients
CB Stehr, R Mellado, MP Ocaranza, CA Carvajal, L Mosso, E Becerra, ...
Journal of hypertension 28 (10), 2120-2126, 2010
1012010
Recent insights and therapeutic perspectives of angiotensin-(1–9) in the cardiovascular system
MP Ocaranza, L Michea, M Chiong, CF Lagos, S Lavandero, JE Jalil
Clinical Science 127 (9), 549-557, 2014
792014
Protective role of the ACE2/Ang-(1–9) axis in cardiovascular remodeling
MP Ocaranza, JE Jalil
International journal of hypertension 2012, 2012
792012
Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1–9) axis in experimental hypertension
MP Ocaranza, P Rivera, U Novoa, M Pinto, L Gonzalez, M Chiong, ...
Journal of hypertension 29 (4), 706-715, 2011
732011
Isoproterenol and angiotensin I-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis
MP Ocaranza, G Díaz-Araya, M Chiong, D Munoz, JP Riveros, ...
Journal of cardiovascular pharmacology 40 (2), 246-254, 2002
562002
Markedly increased Rho-kinase activity in circulating leukocytes in patients with chronic heart failure
MP Ocaranza, L Gabrielli, I Mora, L Garcia, P McNab, I Godoy, S Braun, ...
American heart journal 161 (5), 931-937, 2011
542011
Rho/Rho kinase signal transduction pathway in cardiovascular disease and cardiovascular remodeling
J Jalil, S Lavandero, M Chiong, MP Ocaranza
Revista Española de Cardiología (English Edition) 58 (8), 951-961, 2005
532005
Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension
L Gonzalez, U Novoa, J Moya, L Gabrielli, JE Jalil, L García, M Chiong, ...
Biochemical pharmacology 156, 357-370, 2018
522018
Polymorphism in gene coding for ACE determines different development of myocardial fibrosis in rats
MP Ocaranza, G Díaz-Araya, JE Carreno, D Munoz, JP Riveros, JE Jalil, ...
American Journal of Physiology-Heart and Circulatory Physiology 286 (2 …, 2004
502004
Angiotensin I-converting enzyme modulates neutral endopeptidase activity in the rat
C Oliveri, MP Ocaranza, X Campos, S Lavandero, JE Jalil
Hypertension 38 (3), 650-654, 2001
502001
Increased rho-kinase activity in hypertensive patients with left ventricular hypertrophy
L Gabrielli, JL Winter, I Godoy, P McNab, I Padilla, S Cordova, P Rigotti, ...
American Journal of Hypertension 27 (6), 838-845, 2014
492014
Rho kinase activation and gene expression related to vascular remodeling in normotensive rats with high angiotensin I–converting enzyme levels
P Rivera, MP Ocaranza, S Lavandero, JE Jalil
Hypertension 50 (4), 792-798, 2007
482007
Protection of the myocardium against ischemia/reperfusion injury by angiotensin-(1–9) through an AT2R and Akt-dependent mechanism
E Mendoza-Torres, JA Riquelme, A Vielma, AR Sagredo, L Gabrielli, ...
Pharmacological research 135, 112-121, 2018
422018
Angiotensin I-converting enzyme gene polymorphism influences chronic hypertensive response in the rat Goldblatt model
MP Ocaranza, AM Piddo, P Faúndez, S Lavandero, JE Jalil
Journal of hypertension 20 (3), 413-420, 2002
422002
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