| Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum L Saveanu, O Carroll, V Lindo, M Del Val, D Lopez, Y Lepelletier, F Greer, ... Nature immunology 6 (7), 689-697, 2005 | 574 | 2005 |
| Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM L Fontana, ME Fiori, S Albini, L Cifaldi, S Giovinazzi, M Forloni, R Boldrini, ... PloS one 3 (5), e2236, 2008 | 468 | 2008 |
| Influence of the tumor microenvironment on NK cell function in solid tumors O Melaiu, V Lucarini, L Cifaldi, D Fruci Frontiers in immunology 10, 3038, 2020 | 307 | 2020 |
| Control of cross‐presentation during dendritic cell maturation BC Gil‐Torregrosa, AM Lennon‐Duménil, B Kessler, P Guermonprez, ... European journal of immunology 34 (2), 398-407, 2004 | 191 | 2004 |
| Tumor-infiltrating T lymphocytes improve clinical outcome of therapy-resistant neuroblastoma M Mina, R Boldrini, A Citti, P Romania, V D'Alicandro, M De Ioris, ... Oncoimmunology 4 (9), e1019981, 2015 | 130 | 2015 |
| Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non‐lymphoid human tissues D Fruci, P Giacomini, MR Nicotra, M Forloni, R Fraioli, L Saveanu, ... Journal of cellular physiology 216 (3), 742-749, 2008 | 122 | 2008 |
| Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines D Fruci, S Ferracuti, MZ Limongi, V Cunsolo, E Giorda, R Fraioli, L Sibilio, ... The Journal of Immunology 176 (8), 4869-4879, 2006 | 119 | 2006 |
| Multidrug resistance and cancer stem cells in neuroblastoma and hepatoblastoma A Alisi, WC Cho, F Locatelli, D Fruci International journal of molecular sciences 14 (12), 24706-24725, 2013 | 115 | 2013 |
| Efficient MHC class I-independent amino-terminal trimming of epitope precursor peptides in the endoplasmic reticulum D Fruci, G Niedermann, RH Butler, PM van Endert Immunity 15 (3), 467-476, 2001 | 113 | 2001 |
| Two brc-abl junction peptides bind HLA-A3 molecules and allow specific induction of human cytotoxic T lymphocytes. G Greco, D Fruci, D Accapezzato, V Barnaba, R Nisini, G Alimena, ... Leukemia 10 (4), 693-699, 1996 | 112 | 1996 |
| IRF1 and NF-kB restore MHC class I-restricted tumor antigen processing and presentation to cytotoxic T cells in aggressive neuroblastoma S Lorenzi, M Forloni, L Cifaldi, C Antonucci, A Citti, R Boldrini, M Pezzullo, ... Public Library of Science 7 (10), e46928, 2012 | 103 | 2012 |
| NF-κB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells M Forloni, S Albini, MZ Limongi, L Cifaldi, R Boldrini, MR Nicotra, ... Cancer research 70 (3), 916-924, 2010 | 100 | 2010 |
| Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma FLDF Ombretta Melaiu, Marco Chierici, Valeria Lucarini, Giuseppe Jurman ... Nature Communications, 2020 | 99 | 2020 |
| PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma O Melaiu, M Mina, M Chierici, R Boldrini, G Jurman, P Romania, ... Clinical Cancer Research 23 (15), 4462-4472, 2017 | 98 | 2017 |
| Beyond the proteasome: trimming, degradation and generation of MHC class I ligands by auxiliary proteases L Saveanu, D Fruci, PM van Endert Molecular immunology 39 (3-4), 203-215, 2002 | 97 | 2002 |
| Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer L Cifaldi, P Romania, S Lorenzi, F Locatelli, D Fruci International journal of molecular sciences 13 (7), 8338-8352, 2012 | 95 | 2012 |
| The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: insights from genomic-wide association studies A Fierabracci, A Milillo, F Locatelli, D Fruci Autoimmunity reviews 12 (2), 281-288, 2012 | 87 | 2012 |
| Natural killer cells efficiently reject lymphoma silenced for the endoplasmic reticulum aminopeptidase associated with antigen processing L Cifaldi, E Lo Monaco, M Forloni, E Giorda, S Lorenzi, S Petrini, ... Cancer research 71 (5), 1597-1606, 2011 | 84 | 2011 |
| A role for naturally occurring alleles of endoplasmic reticulum aminopeptidases in tumor immunity and cancer pre-disposition E Stratikos, A Stamogiannos, E Zervoudi, D Fruci Frontiers in oncology 4, 363, 2014 | 80 | 2014 |
| Quantifying recruitment of cytosolic peptides for HLA class I presentation: impact of TAP transport D Fruci, G Lauvau, L Saveanu, M Amicosante, RH Butler, A Polack, ... The Journal of Immunology 170 (6), 2977-2984, 2003 | 72 | 2003 |
