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Kiera Clayton
Kiera Clayton
Ragon Institute of MGH, MIT and Harvard
Dirección de correo verificada de mgh.harvard.edu
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COVID-19-neutralizing antibodies predict disease severity and survival
WF Garcia-Beltran, EC Lam, MG Astudillo, D Yang, TE Miller, J Feldman, ...
Cell 184 (2), 476-488. e11, 2021
6542021
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
YH Huang, C Zhu, Y Kondo, AC Anderson, A Gandhi, A Russell, ...
Nature 517 (7534), 386-390, 2015
6382015
TIGIT marks exhausted T cells, correlates with disease progression, and serves as a target for immune restoration in HIV and SIV infection
GM Chew, T Fujita, GM Webb, BJ Burwitz, HL Wu, JS Reed, ...
PLoS pathogens 12 (1), e1005349, 2016
3382016
Resistance of HIV-infected macrophages to CD8+ T lymphocyte–mediated killing drives activation of the immune system
KL Clayton, DR Collins, J Lengieza, M Ghebremichael, F Dotiwala, ...
Nature immunology 19 (5), 475-486, 2018
1272018
IL-10-producing B cells are induced early in HIV-1 infection and suppress HIV-1-specific T cell responses
J Liu, W Zhan, CJ Kim, K Clayton, H Zhao, E Lee, JC Cao, B Ziegler, ...
PloS one 9 (2), e89236, 2014
1262014
T cell Ig and mucin Domain–Containing protein 3 is recruited to the immune synapse, disrupts stable synapse formation, and associates with receptor phosphatases
KL Clayton, MS Haaland, MB Douglas-Vail, S Mujib, GM Chew, ...
The Journal of Immunology 192 (2), 782-791, 2014
1202014
Antigen-independent induction of Tim-3 expression on human T cells by the common γ-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is …
S Mujib, RB Jones, C Lo, N Aidarus, K Clayton, A Sakhdari, E Benko, ...
The Journal of Immunology 188 (8), 3745-3756, 2012
1122012
HCV‐specific T cells in HCV/HIV co‐infection show elevated frequencies of dual Tim‐3/PD‐1 expression that correlate with liver disease progression
B Vali, RB Jones, A Sakhdari, PM Sheth, K Clayton, FY Yue, G Gyenes, ...
European journal of immunology 40 (9), 2493-2505, 2010
1122010
Tim-3 negatively regulates cytotoxicity in exhausted CD8+ T cells in HIV infection
A Sakhdari, S Mujib, B Vali, FY Yue, S MacParland, K Clayton, RB Jones, ...
PloS one 7 (7), e40146, 2012
1102012
HERV-K–specific T cells eliminate diverse HIV-1/2 and SIV primary isolates
RB Jones, KE Garrison, S Mujib, V Mihajlovic, N Aidarus, DV Hunter, ...
The Journal of clinical investigation 122 (12), 2012
1002012
Soluble T Cell Immunoglobulin Mucin Domain 3 Is Shed from CD8+ T Cells by the Sheddase ADAM10, Is Increased in Plasma during Untreated HIV Infection, and …
KL Clayton, MB Douglas-Vail, AKMN Rahman, KE Medcalf, IY Xie, ...
Journal of virology 89 (7), 3723-3736, 2015
922015
HIV infection of macrophages: implications for pathogenesis and cure
KL Clayton, JV Garcia, JE Clements, BD Walker
Pathogens & immunity 2 (2), 179, 2017
762017
Engineering modular intracellular protein sensor-actuator devices
V Siciliano, B DiAndreth, B Monel, J Beal, J Huh, KL Clayton, ...
Nature communications 9 (1), 1881, 2018
612018
Tim-3 is a marker of plasmacytoid dendritic cell dysfunction during HIV infection and is associated with the recruitment of IRF7 and p85 into lysosomes and with the submembrane …
JA Schwartz, KL Clayton, S Mujib, H Zhang, AKM Rahman, J Liu, FY Yue, ...
The Journal of Immunology 198 (8), 3181-3194, 2017
512017
Correction: Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
YH Huang, C Zhu, Y Kondo, AC Anderson, A Gandhi, A Russell, ...
Nature 536 (7616), 359-359, 2016
392016
Droplet encapsulation improves accuracy of immune cell cytokine capture assays
Y Yuan, J Brouchon, JM Calvo-Calle, J Xia, L Sun, X Zhang, KL Clayton, ...
Lab on a Chip 20 (8), 1513-1520, 2020
362020
HIV-infected macrophages resist efficient NK cell-mediated killing while preserving inflammatory cytokine responses
KL Clayton, G Mylvaganam, A Villasmil-Ocando, H Stuart, MV Maus, ...
Cell host & microbe 29 (3), 435-447. e9, 2021
352021
Expansion of dysfunctional Tim-3–expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques
T Fujita, BJ Burwitz, GM Chew, JS Reed, R Pathak, E Seger, KL Clayton, ...
The journal of immunology 193 (11), 5576-5583, 2014
352014
Stable complex formation between HIV Rev and the nucleosome assembly protein, NAP1, affects Rev function
A Cochrane, LL Murley, M Gao, R Wong, K Clayton, N Brufatto, ...
Virology 388 (1), 103-111, 2009
302009
TIM-3 and its immunoregulatory role in HIV infection
AN Rahman, K Clayton, S Mujib, IW Fong, MA Ostrowski
J Clin Cell Immunol S 7, 007, 2012
92012
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Artículos 1–20