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Ursula Klingmüller
Ursula Klingmüller
Dirección de correo verificada de dkfz-heidelberg.de - Página principal
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Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood
A Raue, C Kreutz, T Maiwald, J Bachmann, M Schilling, U Klingmüller, ...
Bioinformatics 25 (15), 1923-1929, 2009
14012009
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
U Klingmüller, U Lorenz, LC Cantley, BG Neel, HF Lodish
Cell 80 (5), 729-738, 1995
11901995
Comparative proteomic phenotyping of cell lines and primary cells to assess preservation of cell type-specific functions
C Pan, C Kumar, S Bohl, U Klingmueller, M Mann
Molecular & Cellular Proteomics 8 (3), 443-450, 2009
6652009
Identification of nucleocytoplasmic cycling as a remote sensor in cellular signaling by databased modeling
I Swameye, TG Müller, J Timmer, O Sandra, U Klingmüller
Proceedings of the National Academy of Sciences 100 (3), 1028-1033, 2003
4372003
Lessons learned from quantitative dynamical modeling in systems biology
A Raue, M Schilling, J Bachmann, A Matteson, M Schelke, D Kaschek, ...
PloS one 8 (9), e74335, 2013
3842013
Lessons learned from quantitative dynamical modeling in systems biology
A Raue, M Schilling, J Bachmann, A Matteson, M Schelke, D Kaschek, ...
PloS one 8 (9), e74335, 2013
3842013
Interaction of the erythropoietin and stem-cell-factor receptors
H Wu, U Klingmüller, P Besmer, HF Lodish
Nature 377 (6546), 242-246, 1995
3411995
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice
M Castoldi, MV Spasic, S Altamura, J Elmén, M Lindow, J Kiss, J Stolte, ...
The Journal of clinical investigation 121 (4), 1386-1396, 2011
2772011
Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems
A Raue, B Steiert, M Schelker, C Kreutz, T Maiwald, H Hass, J Vanlier, ...
Bioinformatics 31 (21), 3558-3560, 2015
2452015
Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5.
U Klingmüller, S Bergelson, JG Hsiao, HF Lodish
Proceedings of the National Academy of Sciences 93 (16), 8324-8328, 1996
2401996
Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors
U Klingmüller, H Wu, JG Hsiao, A Toker, BC Duckworth, LC Cantley, ...
Proceedings of the National Academy of Sciences 94 (7), 3016-3021, 1997
2171997
Addressing parameter identifiability by model-based experimentation
A Raue, C Kreutz, T Maiwald, U Klingmüller, J Timmer
IET systems biology 5 (2), 120-130, 2011
2102011
Functional interaction of erythropoietin and stem cell factor receptors is essential for erythroid colony formation
H Wu, U Klingmüller, A Acurio, JG Hsiao, HF Lodish
Proceedings of the National Academy of Sciences 94 (5), 1806-1810, 1997
2031997
Covering a broad dynamic range: information processing at the erythropoietin receptor
V Becker, M Schilling, J Bachmann, U Baumann, A Raue, T Maiwald, ...
Science 328 (5984), 1404-1408, 2010
2002010
Hepadnavirus infection requires interaction between the viral pre-S domain and a specific hepatocellular receptor
U Klingmüller, H Schaller
Journal of Virology 67 (12), 7414-7422, 1993
1911993
Simulation methods for optimal experimental design in systems biology
D Faller, U Klingmüller, J Timmer
Simulation 79 (12), 717-725, 2003
1852003
Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1
M Kortylewski, PC Heinrich, A Mackiewicz, U Schniertshauer, ...
Oncogene 18 (25), 3742-3753, 1999
1751999
Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models
RJ Weaver, EA Blomme, AE Chadwick, IM Copple, HHJ Gerets, ...
Nature Reviews Drug Discovery 19 (2), 131-148, 2020
1682020
The glucocorticoid receptor controls hepatic dyslipidemia through Hes1
U Lemke, A Krones-Herzig, MB Diaz, P Narvekar, A Ziegler, ...
Cell metabolism 8 (3), 212-223, 2008
1632008
Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2
F Grebien, MA Kerenyi, B Kovacic, T Kolbe, V Becker, H Dolznig, K Pfeffer, ...
Blood, The Journal of the American Society of Hematology 111 (9), 4511-4522, 2008
1612008
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