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Lorne Zinman
Lorne Zinman
Unknown affiliation
Verified email at sunnybrook.ca
Title
Cited by
Cited by
Year
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
AE Renton, E Majounie, A Waite, J Simón-Sánchez, S Rollinson, ...
Neuron 72 (2), 257-268, 2011
48702011
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1267-1288, 2018
6342018
TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics
IR Mackenzie, AM Nicholson, M Sarkar, J Messing, MD Purice, C Pottier, ...
Neuron 95 (4), 808-816. e9, 2017
5952017
Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis
JO Johnson, EP Pioro, A Boehringer, R Chia, H Feit, AE Renton, ...
Nature neuroscience 17 (5), 664-666, 2014
5442014
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ...
New England Journal of Medicine 383 (2), 109-119, 2020
5012020
First-in-human trial of blood–brain barrier opening in amyotrophic lateral sclerosis using MR-guided focused ultrasound
A Abrahao, Y Meng, M Llinas, Y Huang, C Hamani, T Mainprize, I Aubert, ...
Nature communications 10 (1), 4373, 2019
4482019
Hypermethylation of the CpG island near the G4C2 repeat in ALS with a C9orf72 expansion
Z Xi, L Zinman, D Moreno, J Schymick, Y Liang, C Sato, Y Zheng, M Ghani, ...
The American Journal of Human Genetics 92 (6), 981-989, 2013
3382013
Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form
A Kerman, HN Liu, S Croul, J Bilbao, E Rogaeva, L Zinman, J Robertson, ...
Acta neuropathologica 119, 335-344, 2010
2602010
Bulbar and speech motor assessment in ALS: Challenges and future directions
JR Green, Y Yunusova, MS Kuruvilla, J Wang, GL Pattee, L Synhorst, ...
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14 (7-8), 494-500, 2013
2592013
IV immunoglobulin in patients with myasthenia gravis: a randomized controlled trial
L Zinman, E Ng, V Bril
Neurology 68 (11), 837-841, 2007
2542007
Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: a multi-stage, randomised, double-blind, placebo-controlled trial
ME Cudkowicz, S Titus, M Kearney, H Yu, A Sherman, D Schoenfeld, ...
The Lancet Neurology 13 (11), 1083-1091, 2014
2482014
Pathological heterogeneity in amyotrophic lateral sclerosis with FUS mutations: two distinct patterns correlating with disease severity and mutation
IRA Mackenzie, O Ansorge, M Strong, J Bilbao, L Zinman, LC Ang, ...
Acta neuropathologica 122, 87-98, 2011
2112011
RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS
S Xiao, T Sanelli, S Dib, D Sheps, J Findlater, J Bilbao, J Keith, L Zinman, ...
Molecular and Cellular Neuroscience 47 (3), 167-180, 2011
2032011
Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial
SP Aggarwal, L Zinman, E Simpson, J McKinley, KE Jackson, H Pinto, ...
The Lancet Neurology 9 (5), 481-488, 2010
2012010
Isoform‐specific antibodies reveal distinct subcellular localizations of C 9orf72 in amyotrophic lateral sclerosis
S Xiao, L MacNair, P McGoldrick, PM McKeever, JR McLean, M Zhang, ...
Annals of neurology 78 (4), 568-583, 2015
1882015
Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis
S Bandres‐Ciga, AJ Noyce, G Hemani, A Nicolas, A Calvo, G Mora, ...
Annals of neurology 85 (4), 470-481, 2019
1712019
The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients
Z Xi, M Zhang, AC Bruni, RG Maletta, R Colao, P Fratta, JM Polke, ...
Acta neuropathologica 129 (5), 715-727, 2015
1672015
A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy
M Chitiprolu, C Jagow, V Tremblay, E Bondy-Chorney, G Paris, A Savard, ...
Nature communications 9 (1), 2794, 2018
1662018
Risk of Guillain-Barré syndrome after seasonal influenza vaccination and influenza health-care encounters: a self-controlled study
JC Kwong, PP Vasa, MA Campitelli, S Hawken, K Wilson, LC Rosella, ...
The Lancet Infectious Diseases 13 (9), 769-776, 2013
1622013
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
E Renton Alan, E Majounie, A Waite, J Simón-Sánchez, S Rollinson, ...
Neuron 72 (2), 257-68, 2011
1462011
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