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Lorena Varela-Nallar
Lorena Varela-Nallar
Assistant Professor, Universidad Andres Bello
Dirección de correo verificada de unab.cl
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Wnt signaling in the nervous system and in Alzheimer's disease
NC Inestrosa, L Varela-Nallar
Journal of molecular cell biology 6 (1), 64-74, 2014
3252014
Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses
L Varela-Nallar, IE Alfaro, FG Serrano, J Parodi, NC Inestrosa
Proceedings of the National Academy of Sciences 107 (49), 21164-21169, 2010
2442010
Wnt signaling in the regulation of adult hippocampal neurogenesis
L Varela-Nallar, NC Inestrosa
Frontiers in cellular neuroscience 7, 100, 2013
2072013
Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of A lzheimer's Disease
C Tapia‐Rojas, F Aranguiz, L Varela‐Nallar, NC Inestrosa
Brain Pathology 26 (1), 62-74, 2016
1952016
Wnt signalling in neuronal differentiation and development
NC Inestrosa, L Varela-Nallar
Cell and tissue research 359, 215-223, 2015
1672015
Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer’s disease mice
FJ Bustos, E Ampuero, N Jury, R Aguilar, F Falahi, J Toledo, J Ahumada, ...
Brain 140 (12), 3252-3268, 2017
1382017
Frizzled‐1 is involved in the neuroprotective effect of Wnt3a against Aβ oligomers
MA Chacón, L Varela‐Nallar, NC Inestrosa
Journal of cellular physiology 217 (1), 215-227, 2008
1302008
Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function
L Varela-Nallar, CP Grabowski, IE Alfaro, AR Alvarez, NC Inestrosa
Neural development 4, 1-15, 2009
1242009
Neurobiological effects of Hyperforin and its potential in Alzheimer's disease therapy
TN Griffith, L Varela-Nallar, MC Dinamarca, NC Inestrosa
Current medicinal chemistry 17 (5), 391-406, 2010
1162010
Is there a role for copper in neurodegenerative diseases?
W Cerpa, L Varela-Nallar, AE Reyes, AN Minniti, NC Inestrosa
Molecular aspects of medicine 26 (4-5), 405-420, 2005
992005
Role of Wnt signaling in adult hippocampal neurogenesis in health and disease
SB Arredondo, D Valenzuela-Bezanilla, MD Mardones, L Varela-Nallar
Frontiers in Cell and Developmental Biology 8, 860, 2020
972020
SIRT1 regulates dendritic development in hippocampal neurons
JF Codocedo, C Allard, JA Godoy, L Varela-Nallar, NC Inestrosa
Public Library of Science 7 (10), e47073, 2012
972012
Calcium/calmodulin‐dependent protein kinase type IV is a target gene of the Wnt/β‐catenin signaling pathway
MS Arrázola, L Varela‐Nallar, M Colombres, EM Toledo, F Cruzat, ...
Journal of cellular physiology 221 (3), 658-667, 2009
922009
Induction of cellular prion protein gene expression by copper in neurons
L Varela-Nallar, EM Toledo, LF Larrondo, ALB Cabral, VR Martins, ...
American Journal of Physiology-Cell Physiology 290 (1), C271-C281, 2006
872006
Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance
P Cisternas, P Salazar, FG Serrano, C Montecinos-Oliva, SB Arredondo, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (11 …, 2015
822015
PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors
FJ Bustos, L Varela-Nallar, M Campos, B Henriquez, M Phillips, C Opazo, ...
PLoS One 9 (4), e94037, 2014
812014
Adult hippocampal neurogenesis in aging and Alzheimer's disease
L Varela‐Nallar, FC Aranguiz, AC Abbott, PG Slater, NC Inestrosa
Birth Defects Research Part C: Embryo Today: Reviews 90 (4), 284-296, 2010
742010
Synaptotoxicity in Alzheimer's disease: the Wnt signaling pathway as a molecular target
NC Inestrosa, L Varela‐Nallar, CP Grabowski, M Colombres
IUBMB life 59 (4‐5), 316-321, 2007
742007
Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect …
NC Inestrosa, C Tapia-Rojas, TN Griffith, FJ Carvajal, MJ Benito, ...
Translational psychiatry 1 (7), e20-e20, 2011
732011
Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain of humans and mice exposed to particulate urban air pollution
L Calderón-Garcidueñas, A Herrera-Soto, N Jury, BA Maher, ...
Environmental research 183, 109226, 2020
722020
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