Seguir
Ajit Jadhav
Ajit Jadhav
Dirección de correo verificada de pfizer.com
Título
Citado por
Citado por
Año
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
M Wang, JJ Carver, VV Phelan, LM Sanchez, N Garg, Y Peng, ...
Nature biotechnology 34 (8), 828-837, 2016
32292016
Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries
J Inglese, DS Auld, A Jadhav, RL Johnson, A Simeonov, A Yasgar, ...
Proceedings of the National Academy of Sciences 103 (31), 11473-11478, 2006
8752006
The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics
R Huang, N Southall, Y Wang, A Yasgar, P Shinn, A Jadhav, DT Nguyen, ...
Science translational medicine 3 (80), 80ps16-80ps16, 2011
4242011
A high-throughput screen for aggregation-based inhibition in a large compound library
BY Feng, A Simeonov, A Jadhav, K Babaoglu, J Inglese, BK Shoichet, ...
Journal of medicinal chemistry 50 (10), 2385-2390, 2007
4122007
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
FJ Najm, M Madhavan, A Zaremba, E Shick, RT Karl, DC Factor, TE Miller, ...
Nature 522 (7555), 216-220, 2015
4082015
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells
LA Mathews Griner, R Guha, P Shinn, RM Young, JM Keller, D Liu, ...
Proceedings of the National Academy of Sciences 111 (6), 2349-2354, 2014
4032014
Unexplored therapeutic opportunities in the human genome
TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ...
Nature reviews Drug discovery 17 (5), 317-332, 2018
3602018
Compound cytotoxicity profiling using quantitative high-throughput screening
M Xia, R Huang, KL Witt, N Southall, J Fostel, MH Cho, A Jadhav, ...
Environmental health perspectives 116 (3), 284-291, 2008
3002008
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond
WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ...
PLoS pathogens 12 (7), e1005763, 2016
2942016
Fluorescence spectroscopic profiling of compound libraries
A Simeonov, A Jadhav, CJ Thomas, Y Wang, R Huang, NT Southall, ...
Journal of medicinal chemistry 51 (8), 2363-2371, 2008
2842008
Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors
RS Ferreira, A Simeonov, A Jadhav, O Eidam, BT Mott, MJ Keiser, ...
Journal of medicinal chemistry 53 (13), 4891-4905, 2010
2682010
Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease
A Jadhav, RS Ferreira, C Klumpp, BT Mott, CP Austin, J Inglese, ...
Journal of medicinal chemistry 53 (1), 37-51, 2010
2572010
Pharos: collating protein information to shed light on the druggable genome
DT Nguyen, S Mathias, C Bologa, S Brunak, N Fernandez, A Gaulton, ...
Nucleic acids research 45 (D1), D995-D1002, 2017
2532017
Discovery of a 2, 4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a
F Liu, X Chen, A Allali-Hassani, AM Quinn, GA Wasney, A Dong, ...
Journal of medicinal chemistry 52 (24), 7950-7953, 2009
2462009
Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors
ONF King, XS Li, M Sakurai, A Kawamura, NR Rose, SS Ng, AM Quinn, ...
PloS one 5 (11), e15535, 2010
2432010
A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses
Q Liang, TS Dexheimer, P Zhang, AS Rosenthal, MA Villamil, C You, ...
Nature chemical biology 10 (4), 298-304, 2014
2362014
Characterization of chemical libraries for luciferase inhibitory activity
DS Auld, NT Southall, A Jadhav, RL Johnson, DJ Diller, A Simeonov, ...
Journal of medicinal chemistry 51 (8), 2372-2386, 2008
2362008
Selective and cell-active inhibitors of the USP1/UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells
J Chen, TS Dexheimer, Y Ai, Q Liang, MA Villamil, J Inglese, DJ Maloney, ...
Chemistry & biology 18 (11), 1390-1400, 2011
2252011
Fluorescence polarization assays in high-throughput screening and drug discovery: a review
MD Hall, A Yasgar, T Peryea, JC Braisted, A Jadhav, A Simeonov, ...
Methods and applications in fluorescence 4 (2), 022001, 2016
2182016
Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2, 4-diamino-7-aminoalkoxy-quinazolines.
F Liu, X Chen, A Allali-Hassani, AM Quinn, TJ Wigle, GA Wasney, A Dong, ...
Journal of medicinal chemistry 53 (15), 5844-5857, 2010
2182010
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20